1591 ct evaluation of neonates with seizures attributable to perinatal complications

1591 ct evaluation of neonates with seizures attributable to perinatal complications

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ABSTRACT Although the incidence of neonatal seizures has been reported to be 0.2 - 0.8%, seizures are more prevalent in NICUs. During a 36 month interval, 116 (3%) of all our NICU patients


had one or more seizures. In 75 (65%) patients, these seizures were attributable to perinatal complications, either intracranial hemorrhage or asphyxia, defined as a 5 min. Apgar score of


≤4, and could be divided by age of occurrence into early seizures (<24 hrs of age) and late seizures (>24 hrs of age). 56 of these 75 infants, 26 preterm (PT) and 30 full term (FT)


survived for greater than 72 hrs. 24/26 PT and 24/30 FT infants were evaluated by CT scan. Of those 24 PT infants, 23 had late seizures at an average age of 55 hrs; 22 had intraventricular


hemorrhages (IVH) and l had a subarachnoid hemorrhage (SAH). The other PT infant was asphyxiated and had an early seizure with a normal CT scan. Of the 24 FT infants, 19 had early seizures


at a mean age of 9 hrs. 2 of those infants had subdural hematomas, 3 had focal regions of infarction, and the remaining 15 had normal scans, 5 FT infants had late seizures at a mean age of


56 hrs and had SAH. Thus, although echoencephalography has been found to be extremely useful for the diagnosis of IVH in PT infants, FT neonates with both early and late neonatal seizures


should be evaluated by CT scan for the detection of intracranial lesions requiring immediate and/or close follow-up care. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Yale Univ.


Sch. of Med., Depts. of Pediatrics and Neurology, New Haven, CT. Laura R Merit, Richard M Freedman, Richard A Ehrenkranz & Joseph B Warshaw Authors * Laura R Merit View author


publications You can also search for this author inPubMed Google Scholar * Richard M Freedman View author publications You can also search for this author inPubMed Google Scholar * Richard A


Ehrenkranz View author publications You can also search for this author inPubMed Google Scholar * Joseph B Warshaw View author publications You can also search for this author inPubMed 


Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Merit, L., Freedman, R., Ehrenkranz, R. _et al._ 1591 CT EVALUATION OF NEONATES WITH


SEIZURES ATTRIBUTABLE TO PERINATAL COMPLICATIONS. _Pediatr Res_ 15 (Suppl 4), 708 (1981). https://doi.org/10.1203/00006450-198104001-01608 Download citation * Issue Date: 01 April 1981 *


DOI: https://doi.org/10.1203/00006450-198104001-01608 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable


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