
Understanding lingering symptoms from "long covid"
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Millions of people who have been diagnosed with COVID-19 in the past year have reported new or lingering — and sometimes unusual — symptoms of illness, long after their initial infection. In
fact, it's become so common that clinics have popped up all over the country to study the phenomenon and help these so-called long-haulers get back to normal. Here's what we know
so far about what doctors are calling “long COVID” — and what we are still hoping to learn. IT CAN HAPPEN EVEN IF YOU HAVE A MILD CASE OF COVID-19 When the faculty at the George Washington
(GW) University School of Medicine & Health Sciences launched its COVID-19 Recovery Clinic late last summer, they did so with hospitalized patients in mind, knowing that those who were
severely ill would likely have a longer road to recovery. What the clinic's founders didn't expect, however, was that post-COVID problems were “just as profound” in people who had
mild to moderate cases of the disease, says Monica Lypson, professor of medicine at GW and co-director of its COVID-19 Recovery Clinic. "Right now, the majority of our patients have not
been hospitalized,” she says. This is not unique to GW's clinic. Jennifer Possick, medical director of Yale's Post-COVID Recovery Program, notes a similar trend — and so does Greg
Vanichkachorn at the Mayo Clinic. "We certainly do have some patients that had severe illness or were even in [intensive care], but that's not the majority of our population by
any stretch of the imagination,” says Vanichkachorn, an occupational medical specialist who leads the Mayo Clinic's COVID Activity Rehabilitation Program. A handful of studies support
what health care providers are seeing — that the virus can haunt people who were hardly affected by its initial infection. For example, a July 2020 report from the Centers for Disease
Control and Prevention (CDC) found that 20 percent of previously healthy 18- to 34-year-olds who had COVID-19 and were not hospitalized still weren't back to their usual state of health
two to three weeks after testing positive for a coronavirus infection. Swedish researchers discovered that 26 percent of young and otherwise healthy health care workers who had mild
COVID-19 had at least one moderate to severe symptom for at least two months after their infection; 11 percent had at least one symptom that lasted eight months. Similarly, a pre-print study
looking at health records in California found that 27 percent of people who were never hospitalized for COVID-19 reported ongoing symptoms after 60 days. LONG COVID IS NOT UNCOMMON
It's hard to pinpoint exactly how many people experience new or persistent symptoms after a coronavirus infection, says Mark Avdalovic, a pulmonary and critical care specialist at
University of California Davis Health. But it's something researchers are hoping to better understand. An early study published on long COVID found that more than 87 percent of 143
hospitalized patients with COVID-19 reported at least one persistent symptom following their initial diagnosis. Other reports, however, show that the population affected is likely much
smaller. A U.K.-based survey found that 13.7 percent of more than 20,000 participants who tested positive for COVID-19 continued to experience symptoms for at least 12 weeks after the
infection. Other experts estimate that about 10 percent of the population who had COVID-19 have lingering symptoms. Possick says that since Yale's Post-COVID Recovery Program launched
last summer, she and her colleagues have seen “a lot of traffic” — nearly 500 patients to date. But “that's still a very small number,” considering more than 32 million Americans have
tested positive for COVID-19 and many of them could be battling unrelenting symptoms. "The majority of people with COVID are never hospitalized, and a lot of them are younger,
they're working age. And so even if only a small fraction of those people has persistent post-COVID conditions, mathematically it's still a lot of people,” Possick says.