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A 2017 study published in the _Journal of Smoking Cessation _found that a triple therapy — varenicline combined with the patch and lozenge — can also work well, but the trio approach comes

with a high risk of side effects such as insomnia, strange dreams and nausea. This may be especially pronounced in older adults, who tend to be more sensitive to medications, so Sherman

recommends that you start with just two, and talk to your doctor about adding on if you feel it's needed. PRACTICE MINDFULNESS If hypnosis was the treatment of the 1980s,

mindfulness-based therapies are the smoking cessation approach of the early 21st century. “When nicotine gets into your body through cigarettes, it releases a brain chemical called dopamine,

which makes you feel good,” explains Jud Brewer, M.D., an associate professor in psychiatry at the School of Medicine at Brown University. “Your brain itself has a built-in reward-based

learning system, so each time you smoke, it reinforces a brain pathway that says this is great and do it again." Mindfulness can help you can hijack that reward system and essentially

stub out these cravings, stresses Brewer. One way to do this is to really focus on the sensations of smoking for a few weeks before you officially quit. “When I have patients sit down and

really pay attention to it, they notice the burning feeling as they inhale, and the cigarette's unpleasant taste and smells,” he explains. Once you do quit, every time you experience a

craving to light up, go back to those specific sensations. A study done by Brewer and published in the journal _Drug and Alcohol Dependency_ found that people who participated in mindfulness

training for smoking cessation were about five times more likely to have succeeded at the end of 17 weeks than those who participated in a more traditional smoking cessation program. GET

VIRTUAL SUPPORT Even something as simple as text messages can help you break a habit. Programs like Text2Quit and SmokefreeTXT, which send advice and tips to your cellphone, can more than

double success rates, according to a 2014 study published in the _American Journal of Preventive Medicine_. “Just something as simple as sending out text messages several times a day can

make a big difference, because it keeps you accountable,” explains Sherman. Use of quit apps is another important strategy because you can use them to track cravings, get motivational

messages, find tips and distractions to help you manage cravings and bad moods, even monitor progress toward smoke-free milestones. Try to look for an app that encourages you to accept

smoking triggers (like iCanQuit), rather than just avoid them. Apps that focus on acceptance are almost 50 percent more effective in helping you quit than those that teach avoidance,

according to a study published last year in _JAMA Internal Medicine_. Another option is a mindfulness-based app, like Brewer's To Quit. A study published in 2019 in the journal

_Neuropsychopharmacology_ found that people who used the app for a month reported significantly reduced cravings and lower cigarette consumption than those who used a more traditional

smoking cessation app. BE CAREFUL WITH E-CIGARETTES If you're desperate to stop smoking, you may wonder about switching to e-cigarettes, battery-operated devices that heat nicotine into

a vapor that you breathe in. Since this vapor has fewer toxins than cigarette smoke, it may be considered a safer option than smoking. A 2021 review looked at 56 studies involving nearly

13,000 adults and concluded that nicotine e-cigarettes were more effective at helping people quit smoking than standard treatments such as nicotine replacement therapy, or nicotine-free

e-cigarettes. But e-cigarettes aren't without health risks, as the vapor they generate contains potentially dangerous substances, including lead, volatile organic compounds and

cancer-causing agents. “Often the amount of nicotine found in one e-cigarette is higher than what's in a pack of regular cigarettes,” says Choi. “This can increase your blood pressure

and heart rate, which is very dangerous for someone who already has preexisting heart or lung disease.” Even if you don't have these conditions, e-cigarettes can still carry side

effects such as mouth and throat irritation, headache and cough. “There's also some research to suggest that some people try e-cigarettes as a way to stop smoking, and then end up using

both,” adds Rizzo. That's why groups like the Centers for Disease Control and Prevention and the American Lung Association recommend that you use FDA-approved stop-smoking medications

with proven track records of efficacy and safety rather than e-cigarettes.