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ABSTRACT One of the most common challenges faced by people living with human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) is a low quality of life, particularly

during the coronavirus disease 2019 (COVID-19) pandemic, as they are considered a vulnerable group. This study aimed to examine the relationship between resilience, social support, and

quality of life among people living with HIV/AIDS during the pandemic. Conducted as a cross-sectional study, it involved 433 respondents. Data collection was carried out using a

questionnaire, with Connor–Davidson Resilience Scale-25 (CD-RISC-25), Multidimensional Scale of Perceived Social Support (MSPSS), and World Health Organization Quality of Life–HIV Brief

Version (WHO QoL-HIV-BREF) as the study instruments. The results indicated that resilience and social support were significantly associated with quality of life (p = 0.000; p = 0.000).

Multiple logistic regression analysis identified resilience as the dominant factor influencing quality of life in people living with HIV (OR = 59.533). Respondents with high resilience were

found to have a 59.53 times greater likelihood of experiencing a good quality of life compared to those with medium and low resilience after adjusting for marital status, income status, and

length of time since HIV diagnosis. Resilience plays a crucial role in determining a person’s quality of life. HIV patients who actively participated in foundation-based assistance

demonstrated greater optimism and a more positive acceptance of their condition, enabling them to cope with difficulties better. KEYWORDS: HIV/AIDS, resilience, social support, quality of

life _ABSTRAK_ _RESILIENSI, DUKUNGAN SOSIAL, DAN KUALITAS HIDUP PENDERITA _HIV/AIDS._ Salah satu tantangan yang paling umum dihadapi oleh penderita _HIV/AIDS_ adalah rendahnya kualitas

hidup, terutama saat pandemi _COVID-19,_ karena mereka termasuk dalam kelompok rentan. Penelitian ini bertujuan untuk menguji hubungan antara resiliensi, dukungan sosial, dan kualitas hidup

pada orang dengan _HIV/AIDS_ di masa pandemi. Penelitian ini merupakan penelitian _cross-sectional_ yang melibatkan 433 responden. Pengumpulan data dilakukan dengan menggunakan kuesioner

_Connor–Davidson Resilience Scale-25 (CD-RISC-25), Multidimensional Scale of Perceived Social Support (MSPSS), _dan _World Health Organization Quality of Life–HIV Brief Version (WHO

QoL-HIV-BREF) _sebagai instrumen penelitian. Hasil penelitian menunujukkan bahwa resiliensi dan dukungan sosial memiliki hubungan yang signifikan dengan kualitas hidup (p = 0,000; p =

0,000). Analisis regresi logistik berganda menunjukkan bahwa resiliensi merupakan faktor dominan yang memengaruhi kualitas hidup orang dengan _HIV _(OR = 59,533). Responden dengan resiliensi

tinggi memiliki kemungkinan 59,53 kali lebih besar untuk memiliki kualitas hidup yang baik dibandingkan dengan responden dengan resiliensi sedang dan rendah, setelah mempertimbangkan status

perkawinan, pendapatan, dan durasi sejak didiagnosa _HIV_. Resiliensi berperan penting terhadap kualitas hidup seseorang. Pasien _HIV _yang terlibat aktif dalam mengikuti pendampingan

berbasis lembaga menunjukan sikap yang lebih optimis dan penerimaan yang lebih positif terhadap kondisi mereka, sehingga membuat mereka mampu menghadapi tantangan dengan lebih baik._ _KATA

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