Impact of sugar beet pectin and polydextrose on fasting and postprandial glycemia and fasting concentrations of serum total and lipoprotein lipids in middle-aged subjects with abnormal glucose metabolism

Impact of sugar beet pectin and polydextrose on fasting and postprandial glycemia and fasting concentrations of serum total and lipoprotein lipids in middle-aged subjects with abnormal glucose metabolism


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ABSTRACT OBJECTIVE: To examine the effects of sugar beet pectin (SBP) and polydextrose (PDX) on fasting plasma glucose concentration, serum lipid profile and postprandial glycemia in


middle-aged subjects with abnormal glucose metabolism. DESIGN: A placebo-controlled, randomized, parallel double-blinded study. SUBJECTS AND SETTING: Subjects were recruited via newspaper


announcements. Seventy subjects were recruited of which 66 completed the study. INTERVENTION: The intervention period lasted for 12 weeks during which the subjects consumed a drink enriched


with either SBP (_n_=22) or PDX (_n_=22) or without fiber enrichment (control group, _n_=22). The daily dose of the drinks was 4 dl. The subjects were also given nutrition counseling.


Postprandial glycemia was examined in 24 subjects (_n_=8 in each group) at 0 and 12 weeks after a standardized breakfast. RESULTS: Fasting plasma glucose concentration did not change in the


SBP and PDX groups, whereas it increased in the control group (_P_=0.007). On the contrary, the glycosylated hemoglobin A1c increased marginally but significantly (_P_⩽0.05) in the


intervention groups without a change in the control group. In postprandial glycemia, no differences between the groups were found. In both the SBP and PDX groups, fasting serum High-density


lipoprotein (HDL)-cholesterol concentration increased (_P_⩽0.05) without a change in the control group. Total to HDL-cholesterol ratio decreased in all groups (_P_⩽0.05). CONCLUSIONS: It was


found that SBP and PDX do not have positive effects on fasting or postprandial plasma glucose concentrations or serum lipid profile in subjects with abnormal glucose metabolism.


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245–249. Article  CAS  Google Scholar  Download references ACKNOWLEDGEMENTS We thank laboratory personnel, Ms Päivi Turunen, Mrs Kaija Kettunen, Mrs Eeva Lajunen and Mr Sebastiaan Bol for


excellent technical assistance. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Clinical Nutrition, University of Kuopio and Kuopio University Hospital, Kuopio, Finland U Schwab


* Department of Clinical Nutrition, University of Kuopio, Kuopio, Finland A Louheranta & M Uusitupa * Danisco Ltd, Espoo, Finland A Törrönen Authors * U Schwab View author publications


You can also search for this author inPubMed Google Scholar * A Louheranta View author publications You can also search for this author inPubMed Google Scholar * A Törrönen View author


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AUTHOR Correspondence to U Schwab. ADDITIONAL INFORMATION _Guarantors_: U Schwab and M Uusitupa. _Contributors_: US contributed to study plan, subject recruitment, data analysis and


interpretation, and was the principal author of the manuscript. AL was involved in subject recruitment, counseling of the subjects and data analysis. AT was involved in study plan, planning


of the fiber drinks and data interpretation. MU contributed to study plan and data interpretation. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE


Schwab, U., Louheranta, A., Törrönen, A. _et al._ Impact of sugar beet pectin and polydextrose on fasting and postprandial glycemia and fasting concentrations of serum total and lipoprotein


lipids in middle-aged subjects with abnormal glucose metabolism. _Eur J Clin Nutr_ 60, 1073–1080 (2006). https://doi.org/10.1038/sj.ejcn.1602421 Download citation * Received: 30 June 2005 *


Revised: 21 December 2005 * Accepted: 16 January 2006 * Published: 08 March 2006 * Issue Date: 01 September 2006 * DOI: https://doi.org/10.1038/sj.ejcn.1602421 SHARE THIS ARTICLE Anyone you


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Springer Nature SharedIt content-sharing initiative KEYWORDS * diet * fiber * glucose * human * lipid * pectin