Reader TTS

To examine the effects of sugar beet pectin (SBP) and polydextrose (PDX) on fasting plasma glucose concentration, serum lipid profile and postprandial glycemia in middle-aged subjects with

abnormal glucose metabolism.

A placebo-controlled, randomized, parallel double-blinded study.

Subjects were recruited via newspaper announcements. Seventy subjects were recruited of which 66 completed the study.

The intervention period lasted for 12 weeks during which the subjects consumed a drink enriched with either SBP (n=22) or PDX (n=22) or without fiber enrichment (control group, n=22). The

daily dose of the drinks was 4 dl. The subjects were also given nutrition counseling. Postprandial glycemia was examined in 24 subjects (n=8 in each group) at 0 and 12 weeks after a

standardized breakfast.

Fasting plasma glucose concentration did not change in the SBP and PDX groups, whereas it increased in the control group (P=0.007). On the contrary, the glycosylated hemoglobin A1c increased

marginally but significantly (P⩽0.05) in the intervention groups without a change in the control group. In postprandial glycemia, no differences between the groups were found. In both the

SBP and PDX groups, fasting serum High-density lipoprotein (HDL)-cholesterol concentration increased (P⩽0.05) without a change in the control group. Total to HDL-cholesterol ratio decreased

in all groups (P⩽0.05).

It was found that SBP and PDX do not have positive effects on fasting or postprandial plasma glucose concentrations or serum lipid profile in subjects with abnormal glucose metabolism.

We thank laboratory personnel, Ms Päivi Turunen, Mrs Kaija Kettunen, Mrs Eeva Lajunen and Mr Sebastiaan Bol for excellent technical assistance.

Department of Clinical Nutrition, University of Kuopio and Kuopio University Hospital, Kuopio, Finland

Department of Clinical Nutrition, University of Kuopio, Kuopio, Finland

Contributors: US contributed to study plan, subject recruitment, data analysis and interpretation, and was the principal author of the manuscript.

AL was involved in subject recruitment, counseling of the subjects and data analysis. AT was involved in study plan, planning of the fiber drinks and data interpretation. MU contributed to

study plan and data interpretation.

Anyone you share the following link with will be able to read this content: