Biochemical Tests for Malignancy applied to a New Strain of Human Cells
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TRANSFORMATIONS of normal cells of rats and mice into malignant strains have been reported to occur under tissue culture conditions on a few occasions1, and in such cases it was possible to
demonstrate their malignancy by inoculation into the appropriate animal strains. During tissue-culture experiments with human cells, an abnormal strain appeared in roller-tubes of liver
cells from a 20-week embryo. The new strain showed some of the characteristics of malignant cells, and we had to rely on biochemical tests to obtain further evidence of their malignancy.
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