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ABSTRACT Formyl-methionyl-_t_RNA is bound to ribosomes by single stranded circular DNA of the phage fd. Addition of neomycin _B_ to this complex permits direct translation of this DNA into

protein, which implies that ribosomes do not require a free end on the messenger to initiate protein synthesis. Access through your institution Buy or subscribe This is a preview of

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WITHOUT RIBOSOMES Article 26 July 2021 IN VITRO SYNTHESIS OF 32 TRANSLATION-FACTOR PROTEINS FROM A SINGLE TEMPLATE REVEALS IMPAIRED RIBOSOMAL PROCESSIVITY Article Open access 21 January 2021

INSIGHTS INTO THE RIBOSOME FUNCTION FROM THE STRUCTURES OF NON-ARRESTED RIBOSOME–NASCENT CHAIN COMPLEXES Article 31 October 2022 REFERENCES * McCarthy, B. J., and Holland, J. J., _Proc. US

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AFFILIATIONS * MRC Laboratory of Molecular Biology, Hills Road, Cambridge MARK S. BRETSCHER Authors * MARK S. BRETSCHER View author publications You can also search for this author inPubMed 

Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE BRETSCHER, M. Direct Translation of a Circular Messenger DNA. _Nature_ 220, 1088–1091

(1968). https://doi.org/10.1038/2201088a0 Download citation * Received: 22 November 1968 * Issue Date: 14 December 1968 * DOI: https://doi.org/10.1038/2201088a0 SHARE THIS ARTICLE Anyone you

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