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ABSTRACT THE human embryonic haemoglobins (Hbs) Gower 1 and Gower 2 (ref. 1) are present in fetuses up to 60 mm crown–rump measurement2. However, relatively little is known about the

structure and function of these haemoglobins because of the difficulty in obtaining suitable material, particularly since the introduction of the suction method for terminating pregnancy in

the first trimester. Here we present the amino acid composition and sequence data for the human e-chain, prepared by purifying Hb-Gower 2 (_α_2_ε_2) from early abortion samples. In addition,

separation of embryonic red cells from the majority of the maternal red cells has led to the isolation of Hb-Gower 1 and the demonstration that it has the composition _ζ_2_ε_2. Access

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(in the press). Download references AUTHOR INFORMATION Author notes * J. B. CLEGG: MRC Unit for Molecular Haematology, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford,

UK AUTHORS AND AFFILIATIONS * Department of Clinical Haematology, University College Hospital Medical School, London, WC1, UK R. E. GALE, J. B. CLEGG & E. R. HUEHNS Authors * R. E. GALE

View author publications You can also search for this author inPubMed Google Scholar * J. B. CLEGG View author publications You can also search for this author inPubMed Google Scholar * E.

R. HUEHNS View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE GALE, R.,

CLEGG, J. & HUEHNS, E. Human embryonic haemoglobins Gower 1 and Gower 2. _Nature_ 280, 162–164 (1979). https://doi.org/10.1038/280162a0 Download citation * Received: 14 March 1979 *

Accepted: 23 May 1979 * Published: 01 July 1979 * Issue Date: 12 July 1979 * DOI: https://doi.org/10.1038/280162a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to

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