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ABSTRACT VISUAL information from the retina is transmitted to the cerebral cortex by way of the lateral geniculate nucleus (LGN) in the thalamus. In primates, most of the retinal ganglion

cells that project to the LGN belong to one of two classes, P and M, whose axons terminate in the parvocellular or magnocellular subdivisions of the LGN. These cell classes give rise to two

channels that have been distinguished anatomically, physiologically and behaviourally1–3,16,17. The visual cortex also can be subdivided into two pathways, one specialized for motion

processing and the other for colour and form information4. Several lines of indirect evidence have suggested a close correspondence between the subcortical and cortical pathways, such that

the M channel provides input to the motion pathway and the P channel drives the colour/form pathway5–7. This hypothesis was tested directly by selectively inactivating either the

magnocellular or parvocellular subdivision of the LGN and recording the effects on visual responses in the cortex. We have previously reported that, in accordance with the hypothesis,

responses in the motion pathway in the cortex depend primarily on magnocellular LGN8. We now report that in the colour/form pathway, visual responses depend on both P and M input. These

results argue against a simple correspondence between the subcortical and cortical pathways. Access through your institution Buy or subscribe This is a preview of subscription content,

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PROCESSING OF COHERENT MOTION IN MOUSE VISUAL CORTEX Article Open access 16 July 2020 RAT SUPERIOR COLLICULUS ENCODES THE TRANSITION BETWEEN STATIC AND DYNAMIC VISION MODES Article Open

access 12 February 2024 LATENCY SHORTENING WITH ENHANCED SPARSENESS AND RESPONSIVENESS IN V1 DURING ACTIVE VISUAL SENSING Article Open access 11 April 2022 REFERENCES * Shapley, R. &

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Neurosci._ 5, 321–346 (1990). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Physiology and Center for Visual Science,

University of Rochester, Rochester, New York, 14642-8642, USA Vincent P. Ferrera, Tara A. Nealey & John H. R. Maunsell Authors * Vincent P. Ferrera View author publications You can also

search for this author inPubMed Google Scholar * Tara A. Nealey View author publications You can also search for this author inPubMed Google Scholar * John H. R. Maunsell View author

publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Ferrera, V., Nealey, T. &

Maunsell, J. Mixed parvocellular and magnocellular geniculate signals in visual area V4. _Nature_ 358, 756–758 (1992). https://doi.org/10.1038/358756a0 Download citation * Received: 30 March

1992 * Accepted: 30 June 1992 * Issue Date: 27 August 1992 * DOI: https://doi.org/10.1038/358756a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this

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