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ABSTRACT The 7-repeat allele of the dopamine receptor D4 gene (DRD4) and the 10 repeat allele of the dopamine transporter gene (DAT1) have shown association and linkage with symptoms of

attention deficit hyperactivity disorder (ADHD) in childhood. The parents of ADHD children (clinic group, _n_ = 80 fathers and 107 mothers) and control children (control group, _n_ = 42

fathers and 51 mothers) were the focus of this study. These parents reported retrospectively on their level of ADHD Inattention and Conduct Disorder symptoms in adolescence. In analyses of

the relation of symptom levels to the DRD4 and DAT1 genotypes, fathers possessing the 7 repeat DRD4 allele had greater levels of both inattention and conduct disorder symptoms. Mothers with

the 10/10 genotype had higher levels of inattention symptoms. Thus, genetic associations found in children may be replicable in their parents. Access through your institution Buy or

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GENE – MALTREATMENT INTERPLAY IN ADULT ADHD SYMPTOMS: MAIN ROLE OF A GENE–ENVIRONMENT CORRELATION EFFECT IN A BRAZILIAN POPULATION LONGITUDINAL STUDY Article 14 May 2024 JOINT CONTRIBUTION

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by a grant from the _National Longitudinal Study of Adolescent Health_ (Add Health) consortium to Rowe and by a First Award, K01-HM01818 to Waldman. Add Health was designed by J Richard Udry

and Peter Bearman and is funded by grant P01-HD31921 from the National Institute of Child Health and Human Development. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Graduate Committee in

Genetics and Division of Family Studies and Human Development, Campus Box 210033, University of Arizona, Tucson, 85721, AZ, USA D C Rowe * AOSIS Corporation, 815 W University Drive, Suite

106, Tempe, 85281, AZ, USA C Stever * Department of Molecular and Cellular Biology, University of Arizona, Tucson, 85721, AZ D Chase * Genetics and Molecular Medicine, Emory University,

Atlanta, 30322, GA, USA S Sherman * Department of Psychiatry, Emory University, Atlanta, 30322, GA, USA A Abramowitz * Department of Psychology, Emory University, Atlanta, 30322, GA, USA I D

Waldman Authors * D C Rowe View author publications You can also search for this author inPubMed Google Scholar * C Stever View author publications You can also search for this author

inPubMed Google Scholar * D Chase View author publications You can also search for this author inPubMed Google Scholar * S Sherman View author publications You can also search for this

author inPubMed Google Scholar * A Abramowitz View author publications You can also search for this author inPubMed Google Scholar * I D Waldman View author publications You can also search

for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to D C Rowe. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Rowe, D.,

Stever, C., Chase, D. _et al._ Two dopamine genes related to reports of childhood retrospective inattention and conduct disorder symptoms. _Mol Psychiatry_ 6, 429–433 (2001).

https://doi.org/10.1038/sj.mp.4000874 Download citation * Received: 17 October 2000 * Revised: 02 January 2001 * Accepted: 04 January 2001 * Published: 09 July 2001 * Issue Date: 01 July

2001 * DOI: https://doi.org/10.1038/sj.mp.4000874 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is

not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative KEYWORDS * association * dopamine transporter gene (DAT1) *

dopamine D4 receptor gene (DRD4) * attention deficit hyperactivity disorder (ADHD) * conduct disorder (CD)