Immune-cell block halts brain tumour
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Access through your institution Buy or subscribe A drug that targets the white blood cells fostering brain tumours — rather than the cancer cells themselves — shrinks tumours in mice. The
aggressive brain cancer known as glioblastoma is notoriously difficult to treat. Johanna Joyce at the Memorial Sloan-Kettering Cancer Center in New York and her colleagues gave mice with
glioblastomas a drug that inhibits a cell-surface protein called colony-stimulating factor-1 receptor. This protein is expressed mainly on the white blood cells, or macrophages, that
surround the tumour. This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 51 print issues
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Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Immune-cell block halts brain tumour. _Nature_ 502, 274 (2013). https://doi.org/10.1038/502274b Download citation * Published:
16 October 2013 * Issue Date: 17 October 2013 * DOI: https://doi.org/10.1038/502274b SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get
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