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ABSTRACT BACKGROUND A 59-year-old female presented with a history of recurrent superficial bladder cancer. Since the initial diagnosis 12 years earlier, she had had 12 recurrences, all

treated with transurethral resection with adjuvant bacillus Calmette–Guérin and mitomycin C. Pathology samples had always shown Ta grade 1 transitional-cell carcinoma. At the last

recurrence, she presented with several papillary lesions throughout the bladder, discovered on control cystoscopy. Transurethral resection revealed a papillary grade 3 transitional-cell

carcinoma of the bladder. INVESTIGATIONS Intravenous urography and ureteroscopy. DIAGNOSIS Panurothelial superficial transitional-cell carcinoma. MANAGEMENT Radical cystectomy with total

right ureterectomy and distal left ureterectomy. Reconstruction of the urinary tract was performed with the distal ileum detubulized and rearranged in a U shape. A pyeloileal anastomosis and

a proximal ureteroileal anastomosis were performed at the right and left sides respectively. Access through your institution Buy or subscribe This is a preview of subscription content,

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more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS

OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Jemal A _ et al_. (2005) Cancer statistics, 2005. _CA Cancer J Clin_ 55:

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references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Professor of Urology in the Department of Surgery and Chairman of the Division of Urology at the Hospital das Clínicas at the

University of São Paulo Medical School, Miguel Srougi * Assistant Professors in the Division of Urology and staff members of the Hospital das Clínicas at the University of São Paulo Medical

School in São Paulo, Rua Barata Ribeiro, 414, 7° andar, Bela Vista, São Paulo, 01308–000, SP, Brazil Alberto A Antunes, Marcos F Dall'Oglio & José Cury Authors * Miguel Srougi View

author publications You can also search for this author inPubMed Google Scholar * Alberto A Antunes View author publications You can also search for this author inPubMed Google Scholar *

Marcos F Dall'Oglio View author publications You can also search for this author inPubMed Google Scholar * José Cury View author publications You can also search for this author

inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Miguel Srougi. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing financial interests. RIGHTS AND

PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Srougi, M., Antunes, A., Dall'Oglio, M. _et al._ Management of panurothelial disease in superficial bladder

cancer. _Nat Rev Urol_ 3, 284–288 (2006). https://doi.org/10.1038/ncpuro0489 Download citation * Received: 12 December 2005 * Accepted: 27 March 2006 * Issue Date: 01 May 2006 * DOI:

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