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Access through your institution Buy or subscribe A new study suggests that the way certain medications trigger a hazardous side effect known as 'long QT syndrome' is more complex

than previously thought—a finding that could necessitate changes to drug candidate screening. Long QT syndrome (LQTS) is a condition marked by a lengthening of the QT interval on an

electrocardiogram, typically indicating an excessive lapse between the depolarization and repolarization of the lower chambers of the heart when the organ recharges before the next beat.

Worryingly, this condition puts people at higher risk for a kind of irregular heartbeat called torsade de pointes, which can lead to fainting, palpitations and even sudden death. This is a

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during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support Authors * Roxanne Palmer View author publications You

can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Palmer, R. Paper reveals new channels for worry

over long QT syndrome. _Nat Med_ 18, 839 (2012). https://doi.org/10.1038/nm0612-839a Download citation * Published: 06 June 2012 * Issue Date: June 2012 * DOI:

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