Encoding the unnatural | Nature Methods

Encoding the unnatural | Nature Methods


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Researchers evolved a ribosome that efficiently decodes quadruplet codons, thus opening up the possibility of genetically incorporating multiple unnatural amino acids into proteins. Access


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REFERENCES * Neumann, H. et al. Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome. _Nature_ 464, 441–444 (2010a). Article  CAS  Google Scholar  *


Neumann, H. et al. _De novo_ generation of mutually orthogonal aminoacyl-tRNA synthetase/tRNA pairs. _J. Am. Chem. Soc._ 132, 2142–2144 (2010b). Article  CAS  Google Scholar  Download


references Authors * Allison Doerr View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE


CITE THIS ARTICLE Doerr, A. Encoding the unnatural. _Nat Methods_ 7, 343 (2010). https://doi.org/10.1038/nmeth0510-343 Download citation * Issue Date: May 2010 * DOI:


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