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Blue-light cystoscopy is a method of photodynamic diagnosis (PDD) used in the bladder which offers an opportunity to improve the quality of the endoscopic diagnosis and treatment of bladder

cancer by enhancing the color contrast between tumor and non-tumor tissue. Introduced in Germany1 nearly 20 years ago, a substantial body of evidence, including a recent paper by Geavlete _

et al_.,2 suggests that PDD markedly improves the completeness of the initial resection in transurethral endoscopic surgery. Access through your institution Buy or subscribe This is a

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during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Kriegmair, M. _ et al_. Detection of

early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence. _J. Urol._ 155, 105–110 (1996). Article  CAS  PubMed  Google Scholar  * Geavlete, B., Jecu, M., Multescu, R.,

Georgescu, D. & Geavlete P. HAL blue-light cystoscopy in high-risk nonmuscle-invasive bladder cancer—re-TURBT recurrence rates in a prospective, randomized study. _Urology_ 76, 664–669

(2010). Article  PubMed  Google Scholar  * Babjuk, M. _ et al_. EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder. _Eur. Urol._ 54, 303–314 (2008). Article  PubMed 

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PubMed  Google Scholar  * Stenzl, A. S. _ et al_. Hexvix fluorescence cystoscopy improves detection and resection of papillary bladder cancer and reduces early recurrence: a multicentre

prospective randomized study). _Eur. Urol. Suppl._ 8, 373 (2009). Article  Google Scholar  * Thomas, K. & O'Brien, T. S. Blue sky thinking about blue light cystoscopy. _BJU Int._

104, 887–890 (2009). Article  PubMed  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Urology Center, Guys Hospital, Great Maze Pond, SE1 9RT, London, UK

Tim O'Brien & Kay Thomas Authors * Tim O'Brien View author publications You can also search for this author inPubMed Google Scholar * Kay Thomas View author publications You

can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Tim O'Brien. ETHICS DECLARATIONS COMPETING INTERESTS T. O'Brien and K. Thomas declare

an association with the following company: GE Healthcare (speakers bureau/honoraria). T. O'Brien declares an association with the following company: Photocure (speakers bureau and

grant/research support). RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE O'Brien, T., Thomas, K. Photodynamic diagnosis can improve surgical

outcome. _Nat Rev Urol_ 7, 598–599 (2010). https://doi.org/10.1038/nrurol.2010.183 Download citation * Published: 10 November 2010 * Issue Date: November 2010 * DOI:

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