Why the prostate arm of the PLCO trial failed and what it has taught us

Why the prostate arm of the PLCO trial failed and what it has taught us


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Given a recent update from the PLCO trial reporting that over 90% of men in the 'usual care' arm underwent some degree of PSA testing, the PLCO can no longer accurately be called a trial of


screening versus no screening — nor can it be included as such in meta-analyses or guideline statements.


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