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ABSTRACT From 1961-76, 229 VLBW infants (750-1000 gm) were admitted to the Stanford Intensive Care Nursery . Of these, 144 (63%) died at < 28 days of age; there were 11 late deaths,

including 4 post-discharge. The overall mortality was 68%. Of 74 survivors, 60 with a mean BW of 928±67 (S.D.) gm were followed for 3 years. Thirty-eight % of those followed had a history of

mechanical ventilation; none requiring this prior to 1967 survived. Psychometric testing of 48 children at 3 years of age resulted in a mean IQ of 92±20 (S.D.); using matched-pair analysis,

the mean IQ 90±20 (S.D.), of 28 children was not different from that, 96±18 (S.D.), of their siblings. Seventy-two % of all survivors followed were completely normal at 3 years of age. Of

17 with late morbidity, 10 have moderate handicaps (IQ 60-80, neuromuscular disability requiring physical or orthopedic therapy but not compromising functional independence, or remediable

visual or hearing deficits), and 7 have severe handicaps (IQ < 60, neuromuscular disability compromising functional independence, blindness, or deafness). From 1977-79, the mean yearly

admission rate of VLBW infants was > 2-fold that from 1961-76; this fact was associated with a 76% (75/99) overall survival which was > that, 32% (74/229), prior to 1977 (p < .001).

Our improved survival rate for more infants yearly and our low incidence of severe late morbidity (12%) are encouraging results of intensive care for VLBW infants. ARTICLE PDF AUTHOR

INFORMATION AUTHORS AND AFFILIATIONS * Dept. of Pediatrics, Stanford Univ. School of Medicine, Stanford, Calif. Ronald S Cohen, David K Stevenson, Natalie Malachowski, Andrew O Hopper, Keith

J Kimble, Ronald L Ariagno, John D Johnson & Philip Sunshine Authors * Ronald S Cohen View author publications You can also search for this author inPubMed Google Scholar * David K

Stevenson View author publications You can also search for this author inPubMed Google Scholar * Natalie Malachowski View author publications You can also search for this author inPubMed 

Google Scholar * Andrew O Hopper View author publications You can also search for this author inPubMed Google Scholar * Keith J Kimble View author publications You can also search for this

author inPubMed Google Scholar * Ronald L Ariagno View author publications You can also search for this author inPubMed Google Scholar * John D Johnson View author publications You can also

search for this author inPubMed Google Scholar * Philip Sunshine View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and

permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Cohen, R., Stevenson, D., Malachowski, N. _et al._ 1274 OUTCOME OF VERY LOW BIRTH WEIGHT (VLBW) INFANTS. _Pediatr Res_ 15 (Suppl 4), 655

(1981). https://doi.org/10.1203/00006450-198104001-01303 Download citation * Issue Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-01303 SHARE THIS ARTICLE Anyone you

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