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ABSTRACT Abdominal pain & vomiting are common complaints in adolescents. This is the third case who responded to treatment altering CNS neurotransmitters. Hyperemesis with wt. loss of 25

lbs. occurred in the first month of pregnancy. Recurrent vomiting between 1 & 9 months was diagnosed as plyorospasm & was not relieved by “drops”. At 8 years vomiting started again.

During 40 hospitalizations, all tests were normal. Diagnosis was psychogenic vomiting which was unresponsive to phenobarbital, phentoin or chlorpromazine. During an attack, she had

vomiting, mild abdominal pain, personality change, hypertension, fever, tachycardia, WBC 10-15,000 with high hGH and abnormal EEG, all of which were normal in symptom free periods. From

13-18 years, she had 25 admissions to UTMB including 1 year on a psychiatric unit. Treatment with chlorpromazine, trifluoperazine, phenobarbital, belladona, cyproheptadine or loxipane

failed. Symptoms, lab data & response to previous therapy suggested a deficiency of CNS catechols or dopamine. Amytriptaline 150 mg/d was started to increase the concentration of these

neurotransmitters in CNS. For the next 2 years she had no attacks. Studies during treatment were all normal. 3 weeks after stopping treatment, she had a typical attack. Certain cases of

chronic vomiting may respond to drugs which alter CNS neurotransmitters. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Dept. of Pediatrics and Internal Medicine. University of

Texas Medical Branch., Galveston, Texas Jordan Finkelstein, Cassandra Matustik, Walter Meyer, George Bryan, Michael Ziegler & Michael Anch Authors * Jordan Finkelstein View author

publications You can also search for this author inPubMed Google Scholar * Cassandra Matustik View author publications You can also search for this author inPubMed Google Scholar * Walter

Meyer View author publications You can also search for this author inPubMed Google Scholar * George Bryan View author publications You can also search for this author inPubMed Google Scholar

* Michael Ziegler View author publications You can also search for this author inPubMed Google Scholar * Michael Anch View author publications You can also search for this author inPubMed 

Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Finkelstein, J., Matustik, C., Meyer, W. _et al._ 12 NEUROTRANSMITTER MEDIATED RECURRENT

VOMITING IN A TEENAGE GIRL. _Pediatr Res_ 15 (Suppl 4), 441 (1981). https://doi.org/10.1203/00006450-198104001-00021 Download citation * Issue Date: 01 April 1981 * DOI:

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