Atrial Natriuretic Peptide (ANP) concentrations in infants and children receiving intensive care
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ANP concentrations were measured in 38 children undergoing intensive care. 25 were neonates; 24 with respiratory distress syndrome (RDS) and 5 with patent ductus arteriosus (PDA). 6 infants
with arrhythmias and 7 children who underwent the Fontan procedure were also studied. In all groups median ANP concentration was high, although values fluctuated in patients with RDS or PDA
(median 360 pg/ml, range 0 - 2666 pg/ml, normal range 90 - 240 pg/ml). In these 2 groups there was no significant correlation with plasma or urine sodium concentrations, or fluid intake.
There was a significant positive correlation with arginine vasopressin (AVP) concentrations (p