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ABSTRACT BACKGROUND/OBJECTIVES Maternal psychological distress is associated with a range of adverse child outcomes. We sought to determine whether children’s exposure to medium or severe

distress at 5 years was associated with increased risks of overweight and obesity when they were aged 11 years. We also investigated whether any association was attenuated after accounting

for potential confounding and mediating factors. SUBJECTS/METHODS We analysed data from the UK Millennium Cohort Study, a nationally representative sample with data collected throughout

childhood, imputing missing covariates (analytic sample: _n_ = 9206). Multinomial regression was used to examine whether maternal psychological distress (Kessler-6 scale, using medium and

severe score thresholds) at 5 years of age predicted children’s objectively measured overweight and obesity at 11 years, adjusting for sex and ethnicity. We then carried out a series of

models incorporating potential confounders (early life and socio-demographic, recorded at 9 months) and mediators (physical activity and dietary factors, at 7 years) in turn, and then

simultaneously. RESULTS A third of mothers reported distress when their child was aged 5 years (29% medium; 4% severe distress), and over a quarter of children were overweight at 11 years

(22% overweight; 6% obese). Risks of obesity at 11 years increased with severity of maternal distress at 5 years (medium distress: relative risk ratio (RRR) = 1.43, 95% confidence interval

[CI] 1.17–1.75; severe RRR = 2.27, CI 1.42–3.63). Adjusting for each set of explanatory factors in turn (particularly early years and socio-demographic confounding factors) reduced but did

not eliminate these elevated risks. However, risks were attenuated in the fully adjusted model (medium: RRR = 1.14, CI 0.92–1.41; severe: RRR = 1.26, CI 0.75–2.11). CONCLUSIONS We

demonstrated that maternal psychological distress, particularly if severe, at 5 years was associated with risk of obesity (but not overweight) at 11 years. Accounting for potential

explanatory factors attenuated this association to non-significance, suggesting a range of mechanisms may be implicated. Future research should seek to disentangle the potentially complex

pathways linking explanatory factors, maternal distress and child obesity. SIMILAR CONTENT BEING VIEWED BY OTHERS MATERNAL STRESS AND EARLY CHILDHOOD BMI AMONG US CHILDREN FROM THE

ENVIRONMENTAL INFLUENCES ON CHILD HEALTH OUTCOMES (ECHO) PROGRAM Article 21 July 2023 PSYCHOSOCIAL FACTORS AND THE DEVELOPMENT OF CHILDHOOD OVERWEIGHT AND OBESITY: A UK COHORT STUDY Article

Open access 13 May 2025 PARENTAL ADHD AND ASD SYMPTOMS AND CONTRIBUTIONS OF PSYCHOSOCIAL RISK TO CHILDHOOD ADHD AND ASD SYMPTOMS IN CHILDREN BORN VERY PRETERM Article 15 July 2022

INTRODUCTION The increased prevalence of childhood overweight (including obesity) in high-income countries is a major public health concern, leading to greater risks of morbidity in

childhood and adulthood [1]. The aetiology of childhood overweight is likely to be complex. However, identifying risk factors that are potentially amenable to change may provide

opportunities to develop interventions aimed at reducing levels of overweight [2]. Poor maternal mental health is one such risk factor: it is common in the population (with a lifetime

prevalence of experiencing a major depressive episode ranging between 6 and 17% for women, and higher rates of lower levels of distress [3]), and has been associated with a range of adverse

outcomes in childhood [4, 5], including overweight [6, 7]. A number of mechanisms linking maternal mental health and child overweight have been proposed. There is conflicting evidence on

possible early biological programming (resulting from distress in pregnancy or postpartum) increasing risks for overweight during childhood [8,9,10]. More direct influences on overweight may

arise through a lack of parenting skills [11, 12], which may in turn affect health behaviours [13, 14], including unhealthy feeding practices and diet, lower levels of physical activity,

increased sedentary behaviour and poorer sleep patterns [15,16,17,18]. However, confounding may also be in evidence, with socio-economic disadvantage being a risk both for poor maternal

mental health and childhood overweight [6, 7], while predicting potential mediating factors, such as parenting, diet and physical activity [19, 20]. To date, there has been little

longitudinal research, particularly investigating exposure to maternal mental health problems after infancy. Many studies have been cross-sectional and therefore temporality in the

relationship between maternal mental health and overweight in childhood has not been established. Furthermore, research in this area has tended to rely on non-representative studies with

small sample sizes, and few datasets have included the diverse range of potential mediators and confounders that may underlie this relationship. There is limited evidence differentiating

exposure to medium and severe mental health problems [16, 17], or separating overweight from obesity in the outcome [11, 18, 21]. In addition, US samples have predominated, limiting the

opportunity to understand this relationship in different national contexts. Using longitudinal data from a contemporary UK child cohort (the Millennium Cohort Study, MCS) to capture

temporality during the primary school period of childhood, we sought to determine whether exposure to medium or severe maternal psychological distress when the child was 5 years of age

increased the risk of childhood overweight or obesity at 11 years. In addition, we used the rich data available in the MCS to account for a number of potential explanatory factors, including

confounders (early years and socio-demographic characteristics) recorded at 9 months, and mediators (comprising dietary and physical activity behaviours) recorded at 7 years. Through a

description of patterns of attenuation according to potential explanatory factors, we aimed to provide the basis for further research focusing on testing specific underlying causal pathways

linking maternal psychological distress with childhood overweight and obesity. METHODS SAMPLE The MCS is a large, contemporary cohort of UK children born between 2000 and 2002 which has been

described elsewhere [22]. First contact with the cohort child and main respondent (usually the mother) occurred when the child was 9 months old, when information was collected on 18818

infants (of which we analysed 18296 singletons). At the time of carrying out these analyses, data were available for a further four sweeps, when the children were aged 3, 5, 7 and 11 years,

each receiving approval from a Research Ethics Committee [23]. Data were obtained from the UK Data Archive, University of Essex in March 2014. This paper uses data from 10605 families who

had taken part in the MCS at 9 months, 5 years, 7 years and 11 years, and where the main respondent was the mother. A total of 9206 children had complete data on exposure and outcome

variables, of which 1286 children had missing data on one or more of the explanatory variables. We used multiple imputation by chained equations in 20 datasets to impute missing values for

explanatory variables under a missing at random assumption. MEASURES The temporality of exposure, outcome, and potential mediators and confounders were modelled using MCS data between 9

months and 11 years. Exposure, mediator and outcome variables were drawn from temporally ordered, consecutive sweeps of the MCS, reflecting the years during which the child was in primary

school. The exposure was recorded at 5 years (start of primary school), potential mediators at 7 years, and the outcome at 11 years (the end of primary school). Potential confounders were

measured at 9 months. OUTCOME: OVERWEIGHT OR OBESITY At 11 years, interviewers weighed the children, without shoes or outdoor clothing, using Tanita HD-305 scales (Tanita UK Ltd, Middlesex,

UK). Weights were recorded in kilograms to one decimal place. Heights were obtained by the Leicester Height Measure Stadiometer (Seca Ltd, Birmingham, UK) and recorded to the nearest

millimetre. Children were classified as overweight or obese using International Obesity Task Force (IOTF) international age- and sex-specific cut-offs for body mass index (BMI) [24].

EXPOSURE: MATERNAL PSYCHOLOGICAL DISTRESS At 5 years, mothers completed a widely used and validated measure of psychological distress (the Kessler-6 scale, K-6) [25]. K-6 comprises six-items

asking the mother how often during the past 30 days they felt: “so depressed that nothing could cheer you up”, “hopeless”, “restless or fidgety”, “that everything was an effort”,

“worthless” and “nervous”. Each item had a five-point response, from “None of the time” (0) to “All of the time” (4). Responses to each item were combined to produce a single score ranging

from 0 to 24. Using established cut-offs [26], the score was categorised as medium distress (K-6 score ≥  4) or severe distress (≥13). EXPLANATORY FACTORS Factors that might influence the

relationship between maternal distress at 5 years and child overweight at 11 years, either as potential confounders or mediators, were included in multivariable models. Variables that might

potentially confound the relationship between maternal mental health and childhood overweight included socio-economic status [7] and factors relating to characteristics of the parents and

the early life of the child [6]. Diet and physical activity are important predictors of childhood overweight [27], and have been shown to play a mediating role in the association between

maternal mental distress and childhood overweight [15,16,17,18]. Potential explanatory factors (including categories) are shown in Table 1, and grouped in models as follows. EARLY YEARS

Maternal pre-pregnancy body size (self-reported pre-pregnancy weight and current height, converted to BMI), whether the mother smoked in pregnancy, child’s birthweight (converted to

_z_-scores, adjusting for sex and gestational age), duration of breastfeeding, and whether the child had been introduced to solids before 4 months of age. All early years variables were

recorded at 9 months. SOCIO-DEMOGRAPHICS Maternal highest academic qualification, family structure, and household income quintiles (calculated using a modified OECD equivalence scale). For

the main analysis, all variables were recorded at 9 months. However, family structure and income are potentially time-varying factors. As a sensitivity analysis, analyses were repeated using

values from 7 years (the sweep between exposure and outcome). Child health behaviours that might mediate the relationship between maternal distress at 5 years and child overweight at 11

years were selected from 7-year maternal report. DIET Maternal report of cohort child’s daily consumption of portions of fruit, number of days per week breakfast consumed, consumption of

sweetened drinks between meals, and snacks between meals. PHYSICAL ACTIVITY Maternal report about frequency the child participated in organised sports or activities, non-organised sports or

activities, active play between mother and child, means of transport to school, regularity and timing of bedtime, and number of hours per day the child watched television or videos and used

a computer. Multivariable models also included sex and ethnicity of the cohort child. STATISTICAL ANALYSIS All analyses were conducted in Stata/SE 13 (Stata Corporation, TX), using survey

and non-response weights to account for clustered sampling design and attrition up to 11 years. We calculated percentages (or means) for exposure, explanatory and outcome variables, overall

and by maternal distress and child overweight. We used multinomial logistic regression models to estimate relative risk ratios and 95% confidence intervals (CIs) for childhood weight

(normal, overweight, or obese) at 11 years according to maternal psychological distress when the child was 5 years old. There was no interaction between sex of the child and maternal

distress and therefore analyses were carried out for boys and girls combined. Analyses were carried out using an imputed sample (_n_ = 9206). A sensitivity analysis, which included in the

final model a marker of puberty (maternal report at 11 years of whether the child was reported to have experienced a growth spurt), did not alter the association between maternal distress

and overweight status, either as a main effect or interacting with gender. The models tested were as follows: Model A: Maternal psychological distress + child’s sex and ethnicity Model B: A 

+ early years factors Model C: A + socio-demographic factors Model D: A + dietary factors Model E: A + physical activity factors Model F: Fully adjusted for explanatory factors RESULTS

DESCRIPTIVE STATISTICS A third of mothers (33%) reported distress when their child was aged 5 years, at predominantly medium (29%) rather than severe (4%) levels. At 11 years of age, most

cohort children (72%) were within the normal weight range, with more than a quarter of the children either overweight (22%) or obese (6%). Table 1 shows the relationship between each of the

explanatory factors and BMI weight status at 11 years. Both overweight and obesity at 11 years were predicted by early years and socio-demographic factors recorded at 9 months of age and by

dietary and physical activity factors (with the exception of means of transport to school) at 7 years, although relationships were stronger for obese children. Compared to children who were

normal weight, children who were obese were more likely to have had: a mother with a higher pre-pregnancy BMI, a mother who smoked during pregnancy, a higher birthweight, no or a shorter

period of breastfeeding, and an early introduction to solids. Obese children were also more likely to have been brought up in less advantaged socio-economic circumstances and to have

experienced adverse health behaviours at 7 years (lower fruit consumption, not having a regular breakfast, greater sweetened drink consumption, snacking on crisps, less sport or physical

activity, irregular or late bedtimes, and higher levels of screentime). Most explanatory factors were also associated with maternal distress at 5 years (Supplementary Table S1), including

early factors (except child’s sex and maternal pre-pregnancy BMI), adverse socio-economic circumstances and adverse health behaviours at 7 years. Risks were particularly elevated if the

mother had reported severe distress. REGRESSION MODELS Risk of overweight at 11 years was significantly raised in children whose mothers reported medium levels of psychological distress at 5

years, after accounting for sex and ethnicity (Table 2: Model A). However, this association was attenuated to non-significance in all subsequent models. The association between maternal

distress and obesity was stronger than for overweight, with raised risks for medium and, particularly, severe distress (Model A). Adjusting for early years factors (Model B) and

socio-demographic factors at 9 months of age (Model C) attenuated the association between maternal distress and child obesity, although it remained elevated for both medium and severe

distress. The remaining models accounted for potential mediators between maternal distress and child obesity through child health behaviours recorded at 7 years. As with the early factors,

adjusting for dietary (Model D) and physical activity factors (Model E) attenuated the association between maternal distress and child obesity, although risks remained elevated. Finally, the

association between maternal distress and obesity was attenuated to non-significance for both medium and severe levels of distress when all risk factors were accounted for simultaneously

(Table 2: Model F). Sensitivity analyses carried out with socio-demographic characteristics recorded at 7 years produced similar results (not shown), reflecting continuity in the

socio-economic circumstances of children’s families. DISCUSSION SUMMARY OF FINDINGS In a nationally representative contemporary sample of UK children, maternal distress and childhood

overweight were common. We used longitudinal data to demonstrate that maternal psychological distress at 5 years was associated with increased risks of obesity at 11 years. This was

demonstrated for both medium and severe levels of distress, although severe distress resulted in the greater risk of obesity. Within the MCS, we identified an array of explanatory factors

that might confound or mediate the relationship between maternal mental health and obesity. Perinatal and infancy factors, socio-demographic characteristics, and indicators of the child’s

diet and physical activity were associated with maternal distress at 5 years and child overweight or obesity status at 11 years. Each set of explanatory factors attenuated the association

between maternal distress and childhood obesity to some extent, although only after all potential explanatory factors were accounted for simultaneously were the risks associated with both

medium and severe maternal distress attenuated to non-significance. COMPARISON WITH OTHER FINDINGS The evidence linking maternal mental health problems with childhood overweight and obesity

is inconsistent, with some studies finding that an association exists [6, 7, 28] while others have reported no such association [8, 9, 21]. In accord with some of these studies, we showed a

stronger association between maternal distress and obesity (rather than overweight) [11, 18, 28]. We identified risks for both medium and severe levels of distress, albeit that these risks

were greater for severe distress. Possible mechanisms linking distress with childhood weight have included parenting skills, family feeding practices, and a more sedentary lifestyle

[11,12,13,14,15,16,17,18]. Furthermore, the child’s own mental health may influence their health behaviours and, in turn, increase their risk of overweight or obesity, as has been shown for

children with ADHD [29] or anxiety [30]. In addition, there is a potentially complex interplay between maternal distress and child mental health, whereby the mental health problems of the

child may increase the mother’s distress [31]. Unlike the majority of previous research, we were able to model a plausible temporal sequence between exposure and outcome, adjusting for

confounders measured early in the child’s life and mediators at the intermediate data collection sweep. However, ours was an exploratory study, which aimed to identify areas that would

benefit from further research. STRENGTHS AND LIMITATIONS A major strength of these analyses is the use of the UK Millennium Cohort Study, a large, nationally representative contemporary

cohort. Heights and weights of the children were recorded objectively by interviewers. We used these data to construct a measure of BMI with IOTF cut-offs (for overweight and obesity). This

measure is commonly used in population research, and provides internationally comparable results. In addition, it is relevant for and interpretable by policymakers. Nevertheless, it would

have been informative to also have a measure of central adiposity; unfortunately, this is not available in the MCS. The MCS has detailed information on the early life and socio-demographic

characteristics of the cohort child and their family. However, measures of diet and physical activity available were relatively crude, and there was no suitable measure of parenting

available at 7 years (as a potential mediator between distress and overweight). Maternal distress was measured using the Kessler-6 scale, a widely used, validated scale. Nevertheless, the

K-6, and all explanatory variables were completed by the mother, carrying the potential for report bias. Attrition is always a concern in longitudinal research. Mothers who were identified

as having medium or severe psychological distress at 5 years, or if a child was identified as obese at 11 years, were less likely to have complete data for the analyses. We used multiple

imputation and response weights [32] to account for attrition and item missingness, although results may still have been subject to bias due to these factors. Finally, despite our focus on

maternal distress we acknowledge that risks of childhood overweight and obesity might also be influenced by paternal factors. Nevertheless, mothers are likely to have been the main carers

for children in the period from early to mid-childhood [33, 34], and data on fathers have not been well-measured in the MCS. IMPLICATIONS FOR POLICY AND RESEARCH These results show that

maternal distress recorded at the start of a child’s schooling predicted subsequent obesity in mid-childhood and suggest that multifaceted interventions should be considered for families

where the mother is experiencing distress. Maternal distress is likely to be linked to the mother’s parenting capacities, food and exercise practices, and wider family and social

circumstances. In addition, mothers with mental health problems are more likely themselves to be obese [35]. Factors representing a range of influences, including early years,

socio-demographic circumstances, and dietary and physical activity behaviours were implicated in the development of the association between maternal distress and child obesity over time in

the MCS. Our research has provided a description of diverse influences underlying the relationship between maternal distress and child obesity. Although we were not testing causal pathways,

our findings suggest that no dominant single mechanism or set of explanatory factors can account for the association between maternal distress and child obesity in mid-childhood. This is

consistent with a socio-ecological perspective, acknowledging the multifaceted influences that lead to the development of childhood obesity. This study highlights a number of explanatory

factors on which it would be potentially useful to carry out further research. This might include developing and testing causal models to explicitly identify and test particular confounding

and mediating pathways linking maternal distress and childhood obesity, including the interplay between maternal and child mental health. REFERENCES * Reilly JJ, Kelly J. Long-term impact of

overweight and obesity in childhood and adolescence on morbidity and premature mortality in adulthood: systematic review. Int J Obes. 2011;35:891–8. Article  CAS  Google Scholar  * World

Health Organization. Report of the Commission on Ending Childhood Obesity. WHO: Geneva, Switzerland; 2016. * Goodman SH. Depression in mothers. Annu Rev Clin Psychol. 2007;3:107–35. Article

  Google Scholar  * Turney K. Maternal depression and childhood health inequalities. J Health Soc Behav. 2011;52:314–32. Article  Google Scholar  * Goodman SH, Rouse MH, Connell AM, Broth

MR, Hall CM, Heyward D. Maternal depression and child psychopathology: a meta-analytic review. Clin Child Fam Psychol Rev. 2011;14:1–27. Article  Google Scholar  * Lampard AM, Franckle RL,

Davison KK. Maternal depression and childhood obesity: a systematic review. Prev Med. 2014;59:60–7. Article  Google Scholar  * Hemmingsson E. A new model of the role of psychological and

emotional distress in promoting obesity: conceptual review with implications for treatment and prevention. Obes Rev. 2014;15:769–79. Article  CAS  Google Scholar  * Ingstrup KG, Schou

Andersen C, Ajslev TA, Pedersen P, Sorensen TI, Nohr EA. Maternal distress during pregnancy and offspring childhood overweight. J Obes. 2012;462845:22. Google Scholar  * Ajslev TA, Andersen

CS, Ingstrup KG, Nohr EA, Sorensen TI. Maternal postpartum distress and childhood overweight. PLoS ONE. 2010;5:0011136. Article  CAS  Google Scholar  * Kozyrskyj AL, Zeng Y, Colman I,

HayGlass KT, Sellers EA, Becker AB, et al. Maternal distress in early life predicts the waist-to-hip ratio in schoolchildren. J Dev Orig Health Dis. 2011;2:72–80. Article  CAS  Google

Scholar  * McPhie S, Skouteris H, McCabe M, Ricciardelli LA, Milgrom J, Baur LA, et al. Maternal correlates of preschool child eating behaviours and body mass index: a cross-sectional study.

Int J Pediatr Obes. 2011;6:476–80. Article  Google Scholar  * Wang L, Anderson JL, Dalton Iii WT, Wu T, Liu X, Zheng S. Maternal depressive symptoms and the risk of overweight in their

children. Matern Child Health J. 2013;17:940–8. Article  Google Scholar  * Lampard AM, Jurkowski JM, Lawson HA, Davison KK. Family ecological predictors of physical activity parenting in

low-income families. Behav Med. 2013;39:97–103. Article  Google Scholar  * McCurdy K, Gorman KS, Metallinos-Katsaras E. From poverty to food insecurity and child overweight: a family stress

approach. Child Dev Perspect. 2010;4:144–51. Article  Google Scholar  * Goulding AN, Rosenblum KL, Miller AL, Peterson KE, Chen YP, Kaciroti N, et al. Associations between maternal

depressive symptoms and child feeding practices in a cross-sectional study of low-income mothers and their young children. Int J Behav Nutr Phys Act. 2014;11:1479–5868. Article  Google

Scholar  * Gross RS, Velazco NK, Briggs RD, Racine AD. Maternal depressive symptoms and child obesity in low-income urban families. Acad Pediatr. 2013;13:356–63. Article  Google Scholar  *

Duarte CS, Shen S, Wu P, Must A. Maternal depression and child BMI: longitudinal findings from a US sample. Pediatr Obes. 2012;7:124–33. Article  CAS  Google Scholar  * Morrissey TW, Dagher

RK. A longitudinal analysis of maternal depressive symptoms and children’s food consumption and weight outcomes. Public Health Nutr. 2014;17:2759–68. Article  Google Scholar  * Goisis A,

Sacker A, Kelly Y. Why are poorer children at higher risk of obesity and overweight? A UK cohort study. Eur J Public Health. 2016;26:7–13. Article  Google Scholar  * Parkes A, Sweeting H,

Young R, Wight D. Does parenting help to explain socioeconomic inequalities in children’s body mass index trajectories? Longitudinal analysis using the Growing Up in Scotland study. J

Epidemiol Community Health. 2016;70: 868–73. Article  Google Scholar  * Gibson LY, Byrne SM, Davis EA, Blair E, Jacoby P, Zubrick SR. The role of family and maternal factors in childhood

obesity. Med J Aust. 2007;186:591–5. PubMed  Google Scholar  * Connelly R, Platt L. Cohort profile: UK Millennium Cohort Study (MCS). Int J Epidemiol. 2014;43:1719–25. Article  Google

Scholar  * Hansen K. Millennium Cohort Study: first, second, third, fourth and fifth surveys. London: Centre for Longitudinal Studies; 2014. * Cole TJ, Bellizzi MC, Flegal KM, Dietz WH.

Establishing a standard definition for child overweight and obesity worldwide: international survey. Br Med J. 2000;320:3. Article  Google Scholar  * Kessler RC, Barker PR, Colpe LJ, Epstein

JF, Gfroerer JC, Hiripi E, et al. Screening for serious mental illness in the general population. Arch Gen Psychiatry. 2003;60:184–9. Article  Google Scholar  * Hansen K, Joshi H.

Millennium Cohort Study Second Survey: a user’s guide to initial findings. London: Centre for Longitudinal Studies;2007. * Procter KL. The aetiology of childhood obesity: a review. Nutr Res

Rev. 2007;20:29–45. Article  Google Scholar  * Ramasubramanian L, Lane S, Rahman A. The association between maternal serious psychological distress and child obesity at 3 years: a

cross-sectional analysis of the UK Millennium Cohort Data. Child Care Health Dev. 2013;39:134–40. Article  CAS  Google Scholar  * Waring ME, Lapane KL. Overweight in children and adolescents

in relation to attention-deficit/hyperactivity disorder: results from a national sample. Pediatrics. 2008;122:e1–6. Article  Google Scholar  * Kalarchian MA, Marcus MD. Psychiatric

comorbidity of childhood obesity. Int Rev Psychiatry. 2012;24:241–6. Article  Google Scholar  * Hope S, Pearce A, Chittleborough C, Deighton J, Maika A, Micali N, et al. Temporal effects of

maternal psychological distress on child mental health problems at ages 3, 5, 7 and 11: analysis from the UK Millennium Cohort Study. Psychological Medicine, 2018:1−11.

https://doi.org/10.1017/S0033291718001368 Article  Google Scholar  * Mostafa T. Millennium Cohort Study Technical Report on Response in Sweep 5. London: Centre for Longitudinal Studies,

Institute of Education, University of London; 2014. * Craig L, Mullan K. How mothers and fathers share childcare: a cross-national time-use comparison. Am Sociol Rev. 2011;76:834–61. Article

  Google Scholar  * Bianchi SM, Milkie MA. Work and family research in the first decade of the 21st century. J Marriage Fam. 2010;72:705–25. Article  Google Scholar  * Magallares A,

Pais-Ribeiro JL. Mental health and obesity: a meta-analysis. Appl Res Qual Life. 2014;9:295–308. Article  Google Scholar  Download references ACKNOWLEDGEMENTS The authors thank all the

Millennium Cohort families for their participation, and the director of the Millennium Cohort Study and colleagues in the management team at the Centre for Longitudinal Studies, UCL

Institute of Education. The data for all sweeps are held by the UK Data Service (first survey http://dx.doi.org/10.5255/UKDA-SN-4683-1; second survey http://doi.org/10.5255/UKDA-SN-5350-3;

third survey http://doi.org/10.5255/UKDA-SN-5795-3; fourth survey http://doi.org/10.5255/UKDA-SN-6411-6; fifth survey http://doi.org/10.5255/UKDA-SN-7464-2). The authors also thank members

of the Policy Research Unit in the Health of Children, Young People and Families: Terence Stephenson, Ruth Gilbert, Russell Viner, Miranda Wolpert, Ewan King, Steve Morris, Helen Roberts,

and Enver Solomon, for their comments. FUNDING SH was supported by funding from the Policy Research Unit in the Health of Children, Young People and Families (funding reference 10090001).

The Policy Research Unit in the Health of Children, Young People and Families is funded by the National Institute for Health Research. This paper is based on independent research

commissioned and funded by the National Institute for Health Research Policy Research Programme. The views expressed are those of the authors and not necessarily those of the NHS, the

National Institute for Health Research, the Department of Health and Social Care or its arm’s length bodies, and other Government Departments. JD was supported by the National Institute for

Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care (CLAHRC) North Thames at Bart’s Health NHS Trust. The views expressed are those of the authors and not

necessarily those of the NHS, the NIHR or the Department of Health and Social Care. Research at the UCL Great Ormond Street Institute of Child Health and Great Ormond Street Hospital for

Children receives a proportion of the funding from the Department of Health and Social Care’s National Institute for Health Research Biomedical Research Centres funding scheme. The

Millennium Cohort Study is funded by grants to former and current directors of the study from the Economic and Social Research Council (Professor Heather Joshi, Professor Lucinda Platt and

Professor Emla Fitzsimons) and a consortium of government funders. The study sponsors played no part in the design, data analysis and interpretation of this study; the writing of the

manuscript or the decision to submit the paper for publication, and the authors’ work was independent of their funders. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Population, Policy and

Practice Programme, UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London, WC1N IEH, UK Steven Hope, Nadia Micali & Catherine Law * UCL and Anna Freud National

Centre for Children and Families, 12 Maresfield Gardens, London, NW3 5SU, UK Jessica Deighton Authors * Steven Hope View author publications You can also search for this author inPubMed 

Google Scholar * Nadia Micali View author publications You can also search for this author inPubMed Google Scholar * Jessica Deighton View author publications You can also search for this

author inPubMed Google Scholar * Catherine Law View author publications You can also search for this author inPubMed Google Scholar CONTRIBUTIONS CL initiated the study. All authors

contributed to the study conception. SH designed and conducted the analyses, and drafted the paper. All authors interpreted the results and their implications, have commented on the

manuscript at all stages, and have approved the final submitted version. CORRESPONDING AUTHOR Correspondence to Steven Hope. ETHICS DECLARATIONS CONFLICT OF INTEREST The authors declare that

they have no conflict of interest. ELECTRONIC SUPPLEMENTARY MATERIAL SUPPLEMENTARY TABLE S1 RIGHTS AND PERMISSIONS OPEN ACCESS This article is licensed under a Creative Commons Attribution

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childhood overweight or obesity at 11 years: evidence from the UK Millennium Cohort Study. _Int J Obes_ 43, 43–52 (2019). https://doi.org/10.1038/s41366-018-0252-5 Download citation *

Received: 20 December 2017 * Revised: 11 September 2018 * Accepted: 27 September 2018 * Published: 21 November 2018 * Issue Date: January 2019 * DOI:

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