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ABSTRACT We tested the hypothesis that the maximum value of home systolic BP (MSBP) is a marker of hypertensive target organ damage (TOD). We conducted a cross-sectional study of 220

hypertensives. The subjects performed HBP monitoring using a telemonitoring system and measured their HBP for 7 days. Mean, maximum, standard deviation, and coefficient of variation of SBPs

were used as independent variables. Brachial–ankle pulse wave velocity, left ventricular mass index (LVMI), mean carotid intima–media thickness, and left atrial diameter index (LADI) were

used as dependent variables. Mean and maximum SBPs were significantly associated with each TOD marker. MSBP showed a significantly stronger association with LADI compared to mean SBP (_p_ = 

0.0012) and a significant relationship with LADI independent of LVMI (_p_ = 0.024). Our findings suggest that MSBP is associated with TOD measures, similar to mean SBP. These results may

indicate that MSBP could be a target of intervention for patients with atrial fibrillation. Access through your institution Buy or subscribe This is a preview of subscription content, access

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Cardiovasc Imaging. 2016;32:603–12. Article  PubMed  Google Scholar  Download references ACKNOWLEDGEMENTS We gratefully acknowledge Ms. Matsumoto, Ms. Okura, and Ms. Ochiai for their

coordination and data management of this study and editorial assistance. FUNDING This work was supported by the Japanese Study Group for the Physiology and Management of Blood Pressure by

Omron Healthcare Co., Ltd. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Cardiology, Tokyo Metropolitan Hiroo Hospital, Tokyo, Japan Toshiki Kaihara * Division of

Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan Toshiki Kaihara, Yuki Imaizumi, Kazuo Eguchi & Kazuomi Kario Authors *

Toshiki Kaihara View author publications You can also search for this author inPubMed Google Scholar * Yuki Imaizumi View author publications You can also search for this author inPubMed 

Google Scholar * Kazuo Eguchi View author publications You can also search for this author inPubMed Google Scholar * Kazuomi Kario View author publications You can also search for this

author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Toshiki Kaihara. ETHICS DECLARATIONS CONFLICT OF INTEREST The authors declare that they have no conflict of interest.

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THIS ARTICLE Kaihara, T., Imaizumi, Y., Eguchi, K. _et al._ Maximum home blood pressure readings are associated with left atrial diameter in essential hypertensives. _J Hum Hypertens_ 32,

432–439 (2018). https://doi.org/10.1038/s41371-018-0060-3 Download citation * Received: 29 November 2017 * Revised: 27 February 2018 * Accepted: 05 March 2018 * Published: 01 May 2018 *

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