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Access through your institution Buy or subscribe While there are several factors that contribute to cancer development, mounting evidence suggests that dietary lipids may play an important

role. The idea that what we eat could impact cancer risk has gained attention in recent years, and the lipid-diet-cancer connection has emerged as a promising research field. In fact, there

has been an increasing widespread acceptance of the role played by lipid metabolism in tumor growth, despite its long-standing underestimation. Cancer cells have the ability to acquire,

synthesize, and accumulate fatty acids in the form of lipid droplets [1]. These fatty acids are known to contribute significantly to cancer cell survival in the acidic and hypoxic tumor

microenvironment, and they also promote cell proliferation and invasiveness [1]. Prostate cancer (PCa) is not an exception, and should not be overlooked. In the contemporary urologic

oncology research, there is an increased focus on gaining a thorough understanding of the changes in lipid metabolism in PCa, the regulatory mechanisms responsible for these alterations, and

their significance in both development and progression of the disease, and this in order to develop potential therapeutic strategies [2,3,4]. This is a preview of subscription content,

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OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Snaebjornsson MT, Janaki-Raman S, Schulze A. Greasing the wheels of the

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PubMed Central  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Urology, Hôpital Universitaire de Bruxelles, Brussels, Belgium Georges Mjaess 

& Thierry Roumeguère * Laboratory of Experimental Medicine (ULB 222 Unit), CHU de Charleroi, Hôpital André Vésale, Université libre de Bruxelles (ULB), Montigny-le-Tilleul, Belgium

Thierry Roumeguère & Karim Zouaoui Boudjeltia * Department of Geriatric Medicine, CHU de Charleroi, Hôpital André Vésale, Université libre de Bruxelles (ULB), 6110, Montigny-le-Tilleul,

Belgium Kéziah Korpak * Department-Unit of Pharmacognosy, Bioanalysis and Drug Discovery, Faculty of Pharmacy, Université libre de Bruxelles, Brussels, Belgium Pierre Van Antwerpen Authors *

Georges Mjaess View author publications You can also search for this author inPubMed Google Scholar * Thierry Roumeguère View author publications You can also search for this author

inPubMed Google Scholar * Kéziah Korpak View author publications You can also search for this author inPubMed Google Scholar * Pierre Van Antwerpen View author publications You can also

search for this author inPubMed Google Scholar * Karim Zouaoui Boudjeltia View author publications You can also search for this author inPubMed Google Scholar CONTRIBUTIONS

Conceptualization: GM, TR, KK, KZ. Writing – first draft: GM. Writing – review and editing: GM, TR, KK, PVA, KZ. Supervision: TR, KZ. CORRESPONDING AUTHOR Correspondence to Georges Mjaess.

ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing interests. ADDITIONAL INFORMATION PUBLISHER’S NOTE Springer Nature remains neutral with regard to jurisdictional

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publishing agreement and applicable law. Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Mjaess, G., Roumeguère, T., Korpak, K. _et al._ Fatty acid diet and prostate cancer: a

treasure hunt or a wild goose chase?. _Prostate Cancer Prostatic Dis_ (2024). https://doi.org/10.1038/s41391-024-00854-8 Download citation * Received: 27 April 2024 * Revised: 25 May 2024 *

Accepted: 03 June 2024 * Published: 18 June 2024 * DOI: https://doi.org/10.1038/s41391-024-00854-8 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this

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