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We devised a multiomics strategy to identify metabolic pathways used by yeast to surmount mitochondrial stress. Strains capable of recovery relied on triacylglycerol mobilization to provide

acyl groups for nascent cardiolipin biosynthesis during mitochondrial biogenesis. We further linked multiple proteins to this mobilization phenotype, including essential lipases in both

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remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. THIS IS A SUMMARY OF: Baker, Z. N. et al. Triacylglycerol mobilization underpins

mitochondrial stress recovery. _Nat. Cell Biol_. https://doi.org/10.1038/s41556-024-01586-6 (2025). RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE

Multiomics reveals that triacylglycerol mobilization helps drive recovery from mitochondrial stress. _Nat Cell Biol_ 27, 184–185 (2025). https://doi.org/10.1038/s41556-024-01603-8 Download

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