Ra risk from occupational inhalation

Ra risk from occupational inhalation


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Access through your institution Buy or subscribe Results from a new study have demonstrated that occupational exposure to any of 32 inhalable agents is associated with increased risk of


anti-citrullinated protein antibody (ACPA)-positive rheumatoid arthritis (RA). Among 4,033 patients with incident RA and 6,485 matched individuals without RA, the exposure-associated odds


ratio (OR) for ACPA-positive RA was 1.25, and the risk increased as either the number of agents an individual was exposed to or the duration of exposure increased. Notably, much higher risks


were seen in individuals who had ever smoked and who had high genetic risk scores for RA (OR = 14.80), particularly if they also had occupational exposure to inhalable agents (OR = 18.22).


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ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES ORIGINAL ARTICLE * Tang, B. et al. Occupational inhalable agents


constitute major risk factors for rheumatoid arthritis, particularly in the context of genetic predisposition and smoking. _Ann. Rheum. Dis._ https://doi.org/10.1136/ard-2022-223134 (2022)


Article  PubMed  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Nature Reviews Rheumatology http://www.nature.com/nrrheum/ Robert Phillips Authors * Robert


Phillips View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Robert Phillips. RIGHTS AND PERMISSIONS Reprints and


permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Phillips, R. RA risk from occupational inhalation. _Nat Rev Rheumatol_ 19, 128 (2023). https://doi.org/10.1038/s41584-023-00916-6 Download


citation * Published: 31 January 2023 * Issue Date: March 2023 * DOI: https://doi.org/10.1038/s41584-023-00916-6 SHARE THIS ARTICLE Anyone you share the following link with will be able to


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