
T cell memories of past divisions
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A genetic recorder of T cell replicative history identifies fewer accumulated divisions in a subset of CD8+ central memory T cells that shows stem-cell-like quiescence and superior recall
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taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Bresser, K.
et al. _Nat. Immunol._ https://doi.org/10.1038/s41590-022-01171-9 (2022). Article PubMed Google Scholar * Sarkar, S. et al. _J. Exp. Med._ 205, 625–640 (2008). Article CAS Google
Scholar * Obar, J. J. & Lefrançois, L. _J. Immunol._ 185, 263–272 (2010). Article CAS Google Scholar * Joshi, N. S. et al. _Immunity_ 27, 281–295 (2007). Article CAS Google Scholar
* Kalia, V. et al. _Immunity_ 32, 91–103 (2010). Article CAS Google Scholar * Grassmann, S. et al. _Nat. Immunol._ 170, 2022 (2020). Google Scholar * Pais Ferreira, D. et al.
_Immunity_ 53, 985–1000 (2020). Article CAS Google Scholar * Johnnidis, J. B. et al. _Sci. Immunol._ 6, eabe3702 (2021). Article CAS Google Scholar * Kretschmer, L. et al. _Nat.
Commun._ 11, 113 (2020). Article CAS Google Scholar * Plambeck, M. et al. _Proc. Natl Acad. Sci. USA_ 119, e2116260119 (2022). Article CAS Google Scholar * Youngblood, B. et al.
_Nature_ 552, 404–409 (2017). Article CAS Google Scholar * Herndler-Brandstetter, D. et al. _Immunity_ 48, 716–729 (2018). Article CAS Google Scholar Download references
ACKNOWLEDGEMENTS This work was supported by the European Research Council starting grant 949719-SCIMAP and the Else Kröner-Fresenius-Stiftung grant EKFS 2019_A91 to V.R.B. AUTHOR INFORMATION
AUTHORS AND AFFILIATIONS * Technical University of Munich, School of Medicine, Institute for Medical Microbiology, Immunology and Hygiene, Munich, Germany Lorenz Kretschmer & Veit R.
Buchholz Authors * Lorenz Kretschmer View author publications You can also search for this author inPubMed Google Scholar * Veit R. Buchholz View author publications You can also search for
this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Veit R. Buchholz. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing interests. RIGHTS AND
PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Kretschmer, L., Buchholz, V.R. T cell memories of past divisions. _Nat Immunol_ 23, 646–647 (2022).
https://doi.org/10.1038/s41590-022-01193-3 Download citation * Published: 21 April 2022 * Issue Date: May 2022 * DOI: https://doi.org/10.1038/s41590-022-01193-3 SHARE THIS ARTICLE Anyone you
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