Transcranial Magnetic Stimulation (TMS) – Treatment for Depression

Transcranial Magnetic Stimulation (TMS) – Treatment for Depression


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TMS therapy is an alternative treatment option for patients living with Major Depressive disorder (MDD) that have not achieved a satisfactory response to antidepressant medication. TMS uses


magnetic fields to stimulate nerve cells in the brain to improve symptoms of depression. TMS is safe, non-invasive and effective. TMS has been approved by the FDA since 2008 to treat


depression. TMS is typically used when other depression treatments have not been effective.


MDD is a disabling mental health condition characterized by feelings of sadness or despair, loss of interest in activities, changes in appetite, sleep and energy, and feelings of guilt or


worthlessness. MDD can lead to trouble functioning at work or at home, and can contribute to suicidal thoughts.


During a TMS treatment session, an electromagnetic coil is placed against the scalp. The electromagnet delivers a pulse that stimulates nerve cells in a region of the brain that is involved


in controlling mood. For depression we stimulate the “dorsolateral prefrontal cortex”, one of the major control centers of the brain. Stimulation of this region is thought to enhance its


control of various symptoms of depression.


Antidepressant medications and psychotherapy are the first line treatments for major depression. These treatments, however, do not work for all patients. TMS is often used as an alternative


option to assist with improving depression when medications and therapy have not adequately improved depression symptoms. 


Because TMS uses magnetic pulses, patients must remove any magnetic-sensitive objects (jewelry, hearing aids, credit cards) prior to treatment. Patients are required to wear earplugs during


treatment for their


comfort and for hearing protection, as the TMS device produces a loud clicking noise with each pulse. Patients are seated in a comfortable chair and are awake for the entire session.


During the first session, several measurements are made to ensure the TMS coil will be properly positioned over the correct brain region. The TMS physician measures a “motor threshold” by


administering several brief pulses over the left side of the brain. The motor threshold is the minimum amount of power necessary to make the patient’s thumb twitch, and this varies from


person to person. Measuring the motor threshold helps the physician determine the correct amount of energy required to stimulate the brain.


Once the motor threshold is determined, the coil is placed directly over a brain region called the dorsolateral prefrontal cortex. This area is about the size of a golf ball and is located


towards the front of the brain. Treatment is then started. During the treatment, the device taps on the scalp over this region. The patient can hear a series of clicking sounds and feel a


strong tapping sensation on the scalp.


TMS is prescribed and administered by a TMS-trained psychiatrist. The treatment team will also include a nurse or technician who will assist with treatment sessions.


TMS occurs in a series of treatments. The treatments can vary in length from 3 minutes to 40 minutes, depending on the type of TMS utilized. A typical course of TMS includes at least 30


treatments. Depending on the number of treatments per day, the TMS protocol will last either 1 week or up to 6-8 weeks.


No. TMS does not require any sedation or anesthesia. Patients are fully awake and aware during the treatment. There is no “recovery time” so patients can drive to and from the appointments


and return to their usual activities as soon as the treatment is completed.


TMS is well tolerated and associated with very few side-effects. The most common side-effect (reported in about half of patients) is headaches. These are usually mild and diminish over the


course of treatment.


About one-third of patients may experience painful scalp sensations or facial twitching with TMS pulses. These also tend to improve over the course of treatment. Adjustments can be made


immediately in coil positioning to reduce discomfort.


The TMS device produces a loud clicking noise. Due to this earplugs are required during the treatment. There is no evidence to suggest permanent changes to hearing if earplugs are worn


during treatment.


The most serious risk of TMS is seizures. However the actual risk of a seizure occurring during TMS is exceedingly low. At Montana VA Health Care System, we follow up-to-date safety


guidelines that are designed to minimize the risk of seizures.


Patients with any type of non-removable metal in their heads (with exception of braces or dental fillings). Failure to follow this rule could cause the metal object to heat up, move or


malfunction resulting in serious injury or death.


TMS is one of the alternative options for the treatment of depression offered at Montana VA Health Care System. The first step is to discuss the possibility of TMS with your mental health or


primary care provider. Your provider will submit a consultation request to our clinic and one of our staff members will contact you for an in-person (or video-based) consultation. During


your initial consultation, a thorough medical and mental health history will be taken, to determine if TMS might be safe and appropriate for you. We will also provide detailed information


about TMS, including the treatment process, risks, benefits and side effects. At that time we will be able to answer any questions you might have, prior to you determining if you would like


to proceed with treatment.


Montana VA Transcranial Magnetic Stimulation (TMS) – Treatment for Depression Website


Veterans with PTSD Treated with Transcranial Magnetic Stimulation


TMS has been shown in large, controlled studies to be consistently effective in treating treatment-resistant depression. This means it often works for patients who have not previously


responded to antidepressant medications. The following results were obtained from treating more than 800 veterans with treatment-resistant depression with TMS at outpatient VA clinics across


the country.


VETERANS CRISIS LINE: Dial 988 if you are experiencing suicidal thoughts or an acute mental health crisis (use logo with older male and younger female photo)