Suppression of growth of mouse melanoma by cortisone

Suppression of growth of mouse melanoma by cortisone


Play all audios:


ABSTRACT THE influence of glucocorticoids on the activities of certain enzymes and the part they play in regulating the metabolism of various mammalian tissues have become increasingly


evident in recent years1,2. Harding _et al._3 reported that during the early growth of Walker carcinoma 256 daily treatments with cortisone increased alanine (glutamate-pyruvate)


transaminase activity from its depressed level in the host liver of rats. They also mentioned that the treatment inhibited tumour growth by 68 per cent. Access through your institution Buy


or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 51 print issues and


online access $199.00 per year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes


which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY


OTHERS INTERFERON-GAMMA SIGNALING PROMOTES MELANOMA PROGRESSION AND METASTASIS Article 03 December 2022 THE EFFECT OF RESVERATROL, CURCUMIN AND QUERCETIN COMBINATION ON IMMUNO-SUPPRESSION OF


TUMOR MICROENVIRONMENT FOR BREAST TUMOR-BEARING MICE Article Open access 16 August 2023 STEROID HORMONES AS MODULATORS OF ANTI-TUMOURAL IMMUNITY Article 24 March 2025 REFERENCES * Knox, W.


E., Auerback, V. H., and Lin, E. C. C., _Physiol. Rev._, 49, 164 (1956). Article  Google Scholar  * Weber, G., Singhal, R. L., and Srivastava, S. K., in _Adv. in Enzyme Regulation_, 3 (edit.


by Weber, G.), 43 (Pergamon Press, Oxford, 1965). Google Scholar  * Harding, H. R., Rosen, F., and Nichol, C. A., _Cancer Res._, 24, 1318 (1964). PubMed  CAS  Google Scholar  * Drury, D.


R., _J. Clin. Endocrinol._, 2, 421 (1942). Article  CAS  Google Scholar  * Ingle, D. J., _Endocrinology_, 31, 419 (1942). Article  CAS  Google Scholar  * Bullough, W. S., _Vitamins and


Hormones_, 13, 261 (1955). Article  CAS  Google Scholar  * Munck, A., and Komitz, S. B., _Biochim. Biophys. Acta_, 57, 310 (1962). Article  CAS  Google Scholar  * Morita, Y., and Munck, A.,


_Biochim. Biophys. Acta_, 93, 150 (1964). Article  CAS  Google Scholar  * Lowry, O. H., and Passonneau, J. V., _J. Biol. Chem._, 239, 31 (1964). PubMed  CAS  Google Scholar  * Im, M. J. C.,


and Adachi, K., _J. Invest. Dermatol._, 47, 121 (1966). Article  CAS  Google Scholar  * Adachi, K., and Yamasawa, S., _J. Invest. Dermatol._, 46, 473 (1966). Article  CAS  Google Scholar  *


Wroblewski, F., and LaDu, J. S., _Proc. Soc. Exp. Biol. and Med._, 91, 567 (1956). Article  Google Scholar  * Adachi, K., Lewis, C., and Hershey, F. B., _J. Invest. Dermatol._, 49, 240


(1967). Article  CAS  Google Scholar  * Lowry, O. H., Rosebrough, N. R., Farr, A. L., and Randall, R. J., _J. Biol. Chem._, 193, 265 (1956). Google Scholar  * Adachi, K., in _Advances in


Biology of Skin_, 8 (edit. by Montagna, W., and Hu, F.), 223 (Pergamon Press, Oxford, 1966). Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of


Cutaneous Biology, Oregon Regional Primate Research Center, Beaverton, Oregon KENJI ADACHI, SHIGEO KONDO & FUNAN HU Authors * KENJI ADACHI View author publications You can also search


for this author inPubMed Google Scholar * SHIGEO KONDO View author publications You can also search for this author inPubMed Google Scholar * FUNAN HU View author publications You can also


search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE ADACHI, K., KONDO, S. & HU, F. Suppression of Growth


of Mouse Melanoma by Cortisone. _Nature_ 220, 1132–1133 (1968). https://doi.org/10.1038/2201132a0 Download citation * Received: 28 October 1968 * Issue Date: 14 December 1968 * DOI:


https://doi.org/10.1038/2201132a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently


available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative