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ABSTRACT SOME heterologous antilymphocyte serum (ALS) and plasma (ALP) preparations have immunosuppressive properties1–5 while others, produced in an identical manner, completely lack this

activity5. At present, no in vitro standardization test correlates well with the immunosuppressive potency of ALS or ALP as determined by its ability to prolong allograft survival5–7. The

series of experiments reported here could provide a rational basis for the development of such a test. Access through your institution Buy or subscribe This is a preview of subscription

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ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS EFFECT OF INTRAVENOUS IMMUNOGLOBULIN

(IVIG) ON PRIMATE COMPLEMENT-DEPENDENT CYTOTOXICITY OF GENETICALLY ENGINEERED PIG CELLS: RELEVANCE TO CLINICAL XENOTRANSPLANTATION Article Open access 16 July 2020 C3 COMPLEMENT INHIBITION

PREVENTS ANTIBODY-MEDIATED REJECTION AND PROLONGS RENAL ALLOGRAFT SURVIVAL IN SENSITIZED NON-HUMAN PRIMATES Article Open access 15 September 2021 B CELL DEPLETION WITH ANTI-CD20 MAB

EXACERBATES ANTI-DONOR CD4+ T CELL RESPONSES IN HIGHLY SENSITIZED TRANSPLANT RECIPIENTS Article Open access 13 September 2021 REFERENCES * Woodruff, M. F. A., and Anderson, N. F., _Ann. NY

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AFFILIATIONS * Department of Experimental Surgery, McGill University, Montreal, Canada H. F. JEEJEEBHOY & A. G. RABBAT Authors * H. F. JEEJEEBHOY View author publications You can also

search for this author inPubMed Google Scholar * A. G. RABBAT View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and

permissions ABOUT THIS ARTICLE CITE THIS ARTICLE JEEJEEBHOY, H., RABBAT, A. _In vivo_ Antibody Production by Spleen Cells after Incubation _in vitro_ with Heterologous Antilymphocyte Plasma.

_Nature_ 220, 1350–1352 (1968). https://doi.org/10.1038/2201350a0 Download citation * Received: 10 September 1968 * Revised: 07 November 1968 * Issue Date: 28 December 1968 * DOI:

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