Cells poised to divide can delay their commitment to proliferate
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* RESEARCH BRIEFINGS * 21 August 2024 For a cell to progress through the G1 phase of the cell cycle and divide, it must first integrate various signals. It emerges that cells in a ‘primed’
G1 state — characterized by intermediate activation of a transcription factor called E2F — can hold off making this commitment or even reverse back into G1.