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Antibody surrogates click into place Thomas Kodadek1  Nature Chemistry volume 1, pages 183–185 (2009)Cite this article

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Using the protein of interest as a template, weakly binding ligands can be chemically linked to produce protein-binding agents that can compete with nature's own.

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ways that proximity-mediated 'click' chemistry has been used to identify high-affinity bivalent protein ligands. References Kodadek, T., Reddy, M. M., Olivos, H. J., Bachhawat-Sikder, K. &

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Author informationAuthors and Affiliations Thomas Kodadek is in the Department of Chemistry and the Department of Cancer Biology at the Scripps Florida Research Institute, 130 Scripps Way,

Jupiter, Forida 33458, USA. [email protected],

Thomas Kodadek

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About this articleCite this article Kodadek, T. Antibody surrogates click into place. Nature Chem 1, 183–185 (2009). https://doi.org/10.1038/nchem.228

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Issue Date: June 2009

DOI: https://doi.org/10.1038/nchem.228

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