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Access through your institution Buy or subscribe boxed-textAtes A _ et al_. (2007) Predictive value of antibodies to cyclic citrullinated peptide in patients with early arthritis. _Clin

Rheumatol_ 26: 499–504 The anti-CCP test is highly specific for RA, and a positive result can predict the development of RA in patients with undifferentiated arthritis; the sensitivity of

anti-CCP test, however, is only moderate This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal

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REFERENCES * Avouac J _ et al_. (2006) Diagnostic and predictive value of anti-cyclic citrullinated protein antibodies in rheumatoid arthritis: a systematic literature review. _Ann Rheum

Dis_ 65: 845–851 Article  CAS  Google Scholar  * Dörner T _ et al_. (2004) Rheumatoid factor revisited. _Curr Opin Rheumatol_ 16: 246–253 Article  Google Scholar  * van Gaalen FA _ et al_.

(2004) Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis: a prospective cohort study. _Arthritis Rheum_

50: 709–715 Article  CAS  Google Scholar  * Coenen D _ et al_. (2007) Technical and diagnostic performance of 6 assays for the measurement of citrullinated protein/peptide antibodies in the

diagnosis of rheumatoid arthritis. _Clin Chem_ 53: 498–504 Article  CAS  Google Scholar  Download references ACKNOWLEDGEMENTS The synopsis was written by Jasmine Farsarakis, Associate

Editor, Nature Clinical Practice. AUTHOR INFORMATION Author notes * Department of Rheumatology, Leiden University Medical Centre, PO Box 9600 2300 RC Leiden, The Netherlands

[email protected] AUTHORS AND AFFILIATIONS * FA van Gaalen is a Researcher and a physician in the Departments of Internal Medicine and Rheumatology at the Leiden University Medical

Centre, The Netherlands., Floris A van Gaalen Authors * Floris A van Gaalen View author publications You can also search for this author inPubMed Google Scholar ETHICS DECLARATIONS COMPETING

INTERESTS The author declares no competing financial interests. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE van Gaalen, F. Testing for antibodies to

cyclic citrullinated peptides and rheumatoid factor—what is best for early RA?. _Nat Rev Rheumatol_ 3, 488–489 (2007). https://doi.org/10.1038/ncprheum0565 Download citation * Received: 06

May 2007 * Accepted: 21 May 2007 * Published: 17 July 2007 * Issue Date: September 2007 * DOI: https://doi.org/10.1038/ncprheum0565 SHARE THIS ARTICLE Anyone you share the following link

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