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A selection of abstracts of clinically relevant papers from other journals. The abstracts on this page have been chosen and edited by JOHN R. RADFORD. ABSTRACT No association between

enamel-formation genes and enamel loss (erosion), but there were associations when analysing 'extreme values' for these factors. MAIN Uhlen MM, Stenhagen KR _et al_. _Eur J Oral

Sci_ 2016;124: 426–432 Dental erosion is perplexing. For example, despite acid exposure, not everyone demonstrates erosion. In addition, why do males have a higher prevalence and severity of

erosion than females? The investigators posited that polymorphisms in genes involved in enamel formation, may affect the susceptibility of an individual to erosion. Ninety premolar teeth,

extracted for orthodontic reasons, were subjected to erosive challenge with 0.01M HCl. Fifteen single nucleotide polymorphisms were analysed from salivary DNA. When examining terciles and

quartiles, there were significant associations between erosion and amelogenin (closely related proteins involved in amelogenesis), X-linked tuftelin and tuftelin-interacting protein (may

initiate the enamel mineralisation). Enamel loss was higher in those teeth extracted from males than females. So although females may be genetically less susceptible than males to dental

erosion, simpler explanations may be that merely men exert greater masticatory forces or, as has been shown, women have thicker enamel. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT

THIS ARTICLE CITE THIS ARTICLE Genetic variation may explain why females are less susceptible to dental erosion. _Br Dent J_ 221, 716 (2016). https://doi.org/10.1038/sj.bdj.2016.909 Download

citation * Published: 09 December 2016 * Issue Date: 09 December 2016 * DOI: https://doi.org/10.1038/sj.bdj.2016.909 SHARE THIS ARTICLE Anyone you share the following link with will be able

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