Endothelin signalling drives dermal sheath smooth muscle contraction for hair follicle regression

Endothelin signalling drives dermal sheath smooth muscle contraction for hair follicle regression


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Contraction of the hair follicle-lining dermal sheath smooth muscle generates the forces necessary for the tissue remodelling that takes place during the regression phase of the hair growth


cycle. This study reveals that endothelin signalling — from epithelial progenitors at the follicle bottleneck region to its neighbouring dermal sheath — is the main contraction-activating


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taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Lin, X., Zhu,


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INFORMATION PUBLISHER’S NOTE Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. THIS IS A SUMMARY OF: Martino, P. et al.


Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regression. _Nat. Cell Biol_. https://doi.org/10.1038/s41556-022-01065-w (2023). RIGHTS AND PERMISSIONS


Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Endothelin signalling drives dermal sheath smooth muscle contraction for hair follicle regression. _Nat Cell Biol_ 25, 220–221


(2023). https://doi.org/10.1038/s41556-022-01077-6 Download citation * Published: 30 January 2023 * Issue Date: February 2023 * DOI: https://doi.org/10.1038/s41556-022-01077-6 SHARE THIS


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