Reader TTS

Access through your institution Buy or subscribe New research utilizing time-restricted feeding (TRF) now shows that metabolic homeostasis is maintained as a result of the circadian clock’s

control of daily rhythms in feeding and fasting. Under ad libitum conditions, the control and mutant mice gained weight and exhibited metabolic abnormalities. Importantly, the mutant mice on

TRF were protected from weight gain and metabolic abnormalities. The researchers also conducted extensive transcriptome and metabolome analyses, which showed that TRF reduced the

accumulation of lipids in the liver and enhanced cellular defences against metabolic stress. This is a preview of subscription content, access via your institution ACCESS OPTIONS Access

through your institution Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription $29.99 / 30 days cancel any time Learn more Subscribe to

this journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy

now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer

support REFERENCES ORIGINAL ARTICLE * Chaix, A. et al. Time-restricted feeding prevents obesity and metabolic syndrome in mice lacking a circadian clock. _Cell Metab._

https://doi.org/10.1016/j.cmet.2018.08.004 (2018) Article  PubMed  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Nature Reviews Endocrinology

http://www.nature.com/nrendo/ Claire Greenhill Authors * Claire Greenhill View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR

Correspondence to Claire Greenhill. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Greenhill, C. Benefits of time-restricted feeding. _Nat Rev

Endocrinol_ 14, 626 (2018). https://doi.org/10.1038/s41574-018-0093-2 Download citation * Published: 14 September 2018 * Issue Date: November 2018 * DOI:

https://doi.org/10.1038/s41574-018-0093-2 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not

currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative