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ABSTRACT The amino-acid polymerization factors S1 and S3 form complexes with most aminoacyl-_t_RNA species, including met-_t_RNAM, but not F-met-_t_RNAF and not met-_t_RNAF. This

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* Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS RIBOSOME-MEDIATED POLYMERIZATION OF LONG CHAIN CARBON AND CYCLIC

AMINO ACIDS INTO PEPTIDES IN VITRO Article Open access 27 August 2020 MUTUALLY STABILIZING INTERACTIONS BETWEEN PROTO-PEPTIDES AND RNA Article Open access 19 June 2020 BICYCLOSTREPTINS ARE

RADICAL SAM ENZYME-MODIFIED PEPTIDES WITH UNIQUE CYCLIZATION MOTIFS Article 11 August 2022 REFERENCES * Marcker, K. A., and Sanger, F., _J. Mol. Biol._, 8, 835 (1964). Article  CAS  Google

Scholar  * Marcker, K. A., _J. Mol. Biol._, 14, 63 (1965). Article  CAS  Google Scholar  * Clark, B. F. C., and Marcker, K. A., _J. Mol. Biol._, 17, 394 (1966). Article  CAS  Google Scholar

  * Adams, J. M., and Capecchi, M. R., _Proc. US Nat. Acad. Sci._, 55, 147 (1966). Article  ADS  CAS  Google Scholar  * Webster, R. E., Engelhardt, D. L., and Zinder, N. D., _Proc. US Nat.

Acad. Sci._, 55, 155 (1966). Article  ADS  CAS  Google Scholar  * Capecchi, M. R., _Proc. US Nat. Acad. Sci._, 55, 1517 (1966). Article  ADS  CAS  Google Scholar  * Thach, R. E., Dewey, K.

F., Brown, J. C., and Doty, P., _Science_, 153, 416 (1966). Article  ADS  CAS  Google Scholar  * Sundararajan, T., and Thach, R. E., _J. Mol. Biol._, 19, 74 (1966). Article  CAS  Google

Scholar  * Salas, M., Hille, M. B., Last, J. A., Wahba, A. J., and Ochoa, S., _Proc. US Nat. Acad. Sci._, 57, 387 (1967). Article  ADS  CAS  Google Scholar  * Ghosh, H. P., Söll, D., and

Khorana, H. G., _J. Mol. Biol._, 25, 275 (196 * Lengyel, P., in _Molecular Genetics_, Part II (edit. by Taylor, J. H.), 194 (Academic Press, New York, 1967). Google Scholar  * Marcker, K.

A., Clark, B. F. C., and Anderson, J. S., _Cold Spring Harbor Symp. Quant. Biol._, 31, 279 (1966). Article  CAS  Google Scholar  * Skoultchi, A., Ono, Y., Moon, H. M., and Lengyel, P.,

_Proc. US Nat. Acad. Sci._, 60, 675 (1968). Article  ADS  CAS  Google Scholar  * Gordon, J., _Proc. US Nat. Acad. Sci._, 58, 1574 (1967). Article  ADS  CAS  Google Scholar  * Gordon, J.,

_Proc. US Nat. Acad. Sci._, 59, 179 (1968). Article  ADS  CAS  Google Scholar  * Allende, J. E., Seeds, N. W., Conway, T. W., and Weissbach, H., _Proc. US Nat. Acad. Sci._, 58, 1566 (1967).

Article  ADS  CAS  Google Scholar  * Ertel, R., Brot, N., Redfield, B., Allende, J. E., and Weissbach, H., _Proc. US Nat. Acad. Sci._, 59, 861 (1968). Article  ADS  CAS  Google Scholar  *

Ravel, J. M., Shorey, R. L., Froehner, S., and Shive, N., _Arch. Biochem. Biophys._, 125, 514 (1968). Article  CAS  Google Scholar  * Ravel, J. M., _Proc. US Nat. Acad. Sci._, 57, 1811

(1967). Article  ADS  CAS  Google Scholar  * Lucas-Lenard, J., and Haenni, A., _Proc. US Nat. Acad. Sci._, 59, 554 (1968). Article  ADS  CAS  Google Scholar  * Ono, Y., Skoultchi, A., Klein,

A., and Lengyel, P., _156th ACS National Meeting Abstracts, Division of Biol. Chem._, 239 (1968). * Sundharadas, G., Katze, J. R., Söll, D., Konigsberg, W., and Lengyel, P., _Proc. US Nat.

Acad. Sci._, 61 (in the press). * Adams, J. M., _J. Mol. Biol._, 33, 571 (1968). Article  CAS  Google Scholar  * Dube, S. K., Marcker, K. A., Clark, B. F. C., and Cory, S., _Nature_, 218,

232 (1968). Article  ADS  CAS  Google Scholar  Download references AUTHOR INFORMATION Author notes * ALBRECHT KLEIN Present address: Max-Planck Institut für Virusforschung, Tübingen AUTHORS

AND AFFILIATIONS * Department of Molecular Biophysics, Yale University, YASUSHI ONO, ARTHUR SKOULTCHI, ALBRECHT KLEIN & PETER LENGYEL Authors * YASUSHI ONO View author publications You

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PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE ONO, Y., SKOULTCHI, A., KLEIN, A. _et al._ Peptide Chain Elongation: Discrimination against the Initiator Transfer

RNA by Microbial Amino-acid Polymerization Factors. _Nature_ 220, 1304–1307 (1968). https://doi.org/10.1038/2201304a0 Download citation * Received: 15 October 1968 * Issue Date: 28 December

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